Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms

Linda A. Felton, Ph.D. is a Professor of Pharmaceutics and Chair of the Department of Pharmaceutical Sciences in the College of Pharmacy at the University of New Mexico. She earned a B.S. in Pharmacy and a Ph.D. in Pharmaceutics from the University of Texas at Austin. Her research interests are focused on polymeric film coating and modified release drug delivery systems. She has presented her work at national and international conferences and has published extensively in peer-reviewed journals. Dr. Felton is a reviewer for a number of pharmaceutical journals and an editorial board member of Drug Development and Industrial Pharmacy. She is the Manufacturing Section Editor of the 22nd edition of "Remington: The Science and Practice of Pharmacy", the Co-Editor of the 3rd edition of "Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms", and Editor of ‘Remington: Essentials of Pharmaceutics". Dr. Felton has a joint appointment with the Department of Veteran’s Affairs Cooperative Studies Program where she oversees the formulation development of clinical trials materials. She is a current member of the American Association of Pharmaceutical Scientists, the Controlled Release Society, and the International Society for Pharmaceutical Engineering

Aqueous-based polymeric coating. Pseudolatex dispersions for controlled drug delivery. Processing and equipment considerations for aqueous-based coatings. Mechanical properties of polymeric films prepared from aqueous dispersions. Defects in aqueous film coated solid oral dosage form. Adhesion of polymeric films. Influence of insoluble additives on the properties of polymeric coating systems. Process and formulation factors affecting drug release from pellets coated with ethylcellulose pseudolatex Aquacoat. Chemistry and application properties of polymethacrylate systems. Application of HPMC and HPMCAS to aqueous film coating of pharmaceutical dosage forms. The applications of formulated systems for aqueous film coating of pharmaceutical solid oral dosage forms. *Substrate considerations when developing an aqueous film coated solid oral dosage form. Polymer interactions with drugs and excipients. Physical aging of polymers and it effect on the stability of solid oral dosage forms.