Alzheimer’s Turning Point

Jack C. de la Torre, MD, PhD Professor of Neuropsychology (Adjunct) Department of Psychology University of Texas at Austin, 1 University Station Austin, Texas Dr. Jack de la Torre is a leading authority in the field of Alzheimer's disease (AD). In 1993, he first advanced the concept of AD as a vascular disorder with neurodegenerative consequences in a series of basic and clinical papers that culminated in the CATCH (critically-attained threshold of cerebral hypoperfusion) vascular hypothesis of AD. The vascular hypothesis of AD has had a profound impact and influence on research studies involving epidemiology, neuroimaging, neuropathology and therapeutics that continue to clarify the pathophysiology and pathogenesis of Alzheimer dementia. Dr. de la Torre has edited or co-edited 10 volumes on the subject of vascular factors in AD and published over 200 peer reviewed papers on neurodegeneration, neuropathology and neurotransmission. He has held professorial appointments in the Departments of Neurosurgery at the University of Chicago, Northwestern University, University of Ottawa, and in Pathology at Case Western Reserve University. Dr. de la Torre continues his active research on Alzheimers disease as an Adjunct Professor in the Department of Psychology at the University of Texas at Austin.

Chapter 1 How does Alzheimer's begin and who gets it?.- Chapter 2 Forming memories.- Chapter 3 Masquerading as dementia.- Chapter 4 Alzheimer's --then and now.- Chapter 5 Unproven hypotheses on the cause of Alzheimer's.- Chapter 6 Other hypotheses on the cause of Alzheimer's disease.- Chapter 7 Alzheimer noise.- Chapter 8 Social contract and Alzheimer's.- Chapter 9 Genetics of Alzheimer's.- Chapter 10 Powering the brain.- Chapter 11 Pharmaceuticals and Alzheimer's.- Chapter 12 Alzheimer vascular risk factors.- Chapter 13 The Good, The Bad and The Ugly of Advanced Aging.- Chapter 14 A Personal Account of How a Scientific Hypothesis Blooms Into a Life of Its Own.- Chapter 15 Clinical tools to detect and predict individuals at risk of Alzheimer's.- Chapter 16 The turning point for Alzheimer's.- Chapter 17 How poor brain blood flow promotes Alzheimer's disease.- Chapter 18 Interventions that may increase cerebral blood flow.- Chapter 19 Great Expectations.- Chapter 20 A road to new thinking.