Receptor and Ion-Channel Trafficking
Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels
Seiten
2002
Oxford University Press (Verlag)
978-0-19-263224-1 (ISBN)
Oxford University Press (Verlag)
978-0-19-263224-1 (ISBN)
This book reviews the recent advances in our understanding of the the molecular and cellular mechanisms regulating the targeted movement (trafficking) of receptors and ion channels in neurones - mechanisms fundamental to synaptic function.
A volume in the Molecular and Cellular Neurobiology series.
This book reviews the recent advances in our understanding of the molecular and cellular mechanisms that control the assembly, transport, targeting and anchoring of the protein complexes making up the most important ion channels and receptor families, fundamental to synaptic function. Improved understanding of these processes is expected to reveal novel therapeutic targets relevant to a range of disease states.
The first section of the book contains three chapters dealing with cation channels and provides an accessible, succinct and comprehensive account of what is known about the structures and the assembly and targeting of these multimeric proteins. The focus of the book then moves on to cover ligand-gated ion channels with two chapters on acetylcholine receptors. The final section of the book contains four chapters covering the excitatory and inhibitory amino acid receptors.
Receptor and Ion-Channel Trafficking provides an integrated overview of the significant recent advances in the field of molecular neurobiology and will be essential reading for all researchers in neuroscience, neurobiology, biochemistry, cellular and molecular biology.
A volume in the Molecular and Cellular Neurobiology series.
This book reviews the recent advances in our understanding of the molecular and cellular mechanisms that control the assembly, transport, targeting and anchoring of the protein complexes making up the most important ion channels and receptor families, fundamental to synaptic function. Improved understanding of these processes is expected to reveal novel therapeutic targets relevant to a range of disease states.
The first section of the book contains three chapters dealing with cation channels and provides an accessible, succinct and comprehensive account of what is known about the structures and the assembly and targeting of these multimeric proteins. The focus of the book then moves on to cover ligand-gated ion channels with two chapters on acetylcholine receptors. The final section of the book contains four chapters covering the excitatory and inhibitory amino acid receptors.
Receptor and Ion-Channel Trafficking provides an integrated overview of the significant recent advances in the field of molecular neurobiology and will be essential reading for all researchers in neuroscience, neurobiology, biochemistry, cellular and molecular biology.
ION CHANNELS ; 1. Voltage-gated sodium channels ; 2. The assembly and targeting of potassium channels ; 3. Assembly and targeting of voltage-dependent calcium channels ; ACETYLCHOLINE RECEPTORS ; 4. Targeting of acetylcholine receptors to the postsynaptic endplate of the nerve-muscle synapse ; 5. Assembly and targeting of neuronal nicotinic acetylcholine receptors ; AMINO ACID RECEPTORS ; 6. AMPA/kainate receptors ; 7. NMDA receptor targeting ; 8. Structure, assembly and targeting of glycine receptors ; 9. GABAA and GABAC receptors: regulation of assembly, localization, clustering and turnover
Erscheint lt. Verlag | 1.9.2002 |
---|---|
Reihe/Serie | Molecular and Cellular Neurobiology Series |
Zusatzinfo | numerous halftones and figures |
Verlagsort | Oxford |
Sprache | englisch |
Maße | 174 x 248 mm |
Gewicht | 646 g |
Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
Naturwissenschaften ► Biologie ► Humanbiologie | |
Naturwissenschaften ► Biologie ► Zellbiologie | |
Naturwissenschaften ► Biologie ► Zoologie | |
ISBN-10 | 0-19-263224-8 / 0192632248 |
ISBN-13 | 978-0-19-263224-1 / 9780192632241 |
Zustand | Neuware |
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