Measuring Cell Mechanics
Seiten
2015
Morgan & Claypool Publishers (Verlag)
978-1-61504-698-0 (ISBN)
Morgan & Claypool Publishers (Verlag)
978-1-61504-698-0 (ISBN)
Cells are inherently physical entities that both experience mechanical forces from their external environment and generate their own internal forces to drive cell motion. The aim of this volume is to present the reader with an introduction to the primary tools used to measure these mechanical interactions and the material properties of cells that result from them.
Cells are inherently physical entities that both experience mechanical forces from their external environment and generate their own internal forces to drive cell motion. Our particular aim here is to present the reader with an introduction to the primary tools used to measure these mechanical interactions and the material properties of cells that result from them. These approaches can be applied to a diverse array of physiological processes and systems, providing important insight into the regulatory roles of mechanical interactions in cells. We cover techniques at both the molecular and cellular scales, including those that actively and passively probe the system. Along the way we cover the fundamental principles of each approach, while emphasizing the relevant length and timescales, along with the typical magnitudes of the measurements that can be made. Each section ends by highlighting uses of the various techniques in recent relevant publications, illustrating the exciting future of cell mechanics in quantitative cell biology research.
Cells are inherently physical entities that both experience mechanical forces from their external environment and generate their own internal forces to drive cell motion. Our particular aim here is to present the reader with an introduction to the primary tools used to measure these mechanical interactions and the material properties of cells that result from them. These approaches can be applied to a diverse array of physiological processes and systems, providing important insight into the regulatory roles of mechanical interactions in cells. We cover techniques at both the molecular and cellular scales, including those that actively and passively probe the system. Along the way we cover the fundamental principles of each approach, while emphasizing the relevant length and timescales, along with the typical magnitudes of the measurements that can be made. Each section ends by highlighting uses of the various techniques in recent relevant publications, illustrating the exciting future of cell mechanics in quantitative cell biology research.
University of Chicago University of Chicago
Introduction
Molecular Measurements
Mechanical Properties of Cells
Perturbing Cellular Mechanics
Concluding Remarks
References
Author Biographies
Erscheinungsdatum | 18.03.2016 |
---|---|
Reihe/Serie | Colloquium Series on Quantitative Cell Biology |
Verlagsort | San Rafael |
Sprache | englisch |
Maße | 191 x 235 mm |
Gewicht | 333 g |
Themenwelt | Naturwissenschaften ► Biologie ► Allgemeines / Lexika |
Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
ISBN-10 | 1-61504-698-4 / 1615046984 |
ISBN-13 | 978-1-61504-698-0 / 9781615046980 |
Zustand | Neuware |
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