Organic Chemistry

About our authors L.G. “Skip” Wade received his B.A. from Rice in 1969 and then went on to Harvard University, where he did research with Professor James D. White. While at Harvard, he served as the Head Teaching Fellow for the organic laboratories and was strongly influenced by the teaching methods of two master educators, Professors Leonard K. Nash and Frank H. Westheimer. After completing his Ph.D. at Harvard in 1974, Dr. Wade joined the chemistry faculty at Colorado State University. Over the course of fifteen years at Colorado State, Dr. Wade taught organic chemistry to thousands of students working toward careers in all areas of biology, chemistry, human medicine, veterinary medicine, and environmental studies. He also authored research papers in organic synthesis and in chemical education, as well as eleven books reviewing current research in organic synthesis. Since 1989, Dr. Wade has been a chemistry professor at Whitman College, where he teaches organic chemistry and pursues interests in organic synthesis and forensic chemistry. Dr. Wade received the A.E. Lange Award for Distinguished Science Teaching at Whitman in 1993. Jan Simek was born to humble coal-mining parents who taught him to appreciate the importance of carbon at a very early age. At age 14, he was inspired to pursue a career teaching chemistry by his high school chemistry teacher, Joe Plaskas. Under the guidance of Professor Kurt Kaufman at Kalamazoo College, Dr. Simek began lab work in synthesis of natural products that turned into research in hop extracts for the Kalamazoo Spice Extraction Company. After receiving a master’s degree from Stanford University, Dr. Simek worked in the pharmaceutical industry, synthesizing compounds designed to control diabetes and atherosclerosis, and assisted in the isolation of anti-cancer antibiotics from natural sources. Returning to Stanford University, Dr. Simek completed his Ph.D. with the legendary Professor Carl Djerassi, who developed the first synthesis of steroidal oral contraceptives. Dr. Simek’s 35-year teaching career was spent primarily at California Polytechnic State University, San Luis Obispo, where he received the university’s Distinguished Teaching Award. Other teaching experiences include Albion College, the University of Colorado at Boulder, Kalamazoo College, and the University of California at Berkeley. In addition to his pharmaceutical research, he has industrial experience investigating dyes, surfactants, and liquid crystals, and he continues to consult for the biotechnology industry. Although his outside interests include free climbing in Yosemite, performing in a reggae band, and parasailing over the Pacific, as close as he gets to any of those is tending his backyard garden with his wife Judy.

Structure and Bonding
Acids and Bases: Functional Groups
Structure and Stereochemistry of Alkanes
The Study of Chemical Reactions
Stereochemistry
Alkyl Halides. Nucleophilic Substitution
Structure and Synthesis of Alkenes; Elimination
Reactions of Alkenes
Alkynes
Structure and Synthesis of Alcohols
Reactions of Alcohols
Infrared Spectroscopy and Mass Spectrometry
Nuclear Magnetic Resonance Spectroscopy
Ethers, Epoxides and Thioethers
Conjugated Systems, Orbital Symmetry, and Ultraviolet Spectroscopy
Aromatic Compounds
Reactions of Aromatic Compounds
Ketones and Aldehydes
Amines
Carboxylic Acids
Carboxylic Acid Derivatives
Condensations and Alpha Substitutions of Carbonyl Compounds
Carbohydrates and Nucleic Acids
Amino Acids, Peptides, and Proteins
Lipids
Polymers