Oxidative Stress and Redox Signalling in Parkinson’s Disease

Dr Franco is an Assistant Professor of Neuroscience at the Redox Biology Center, University of Nebraska-Lincoln. Prior to this position, he was post-doctoral fellow at the National Institute of Environmental Health Sciences, USA. His research interests include the role of oxidative stress and redox signaling in the regulation of cell death pathways, and in neuronal cell death associated with neurological disorders. He has been awarded the Layman Award and the SIGMA XI Outstanding Young Scientist Award. Dr Doorn is an Associate Professor of Medicinal and Natural Products Chemistry at the University of Iowa, College of Pharmacy. Before this, he was a post-doctoral fellow at the University of Colorado Health Sciences Center, Depts. of Pharmaceutical Sciences and Pharmacology, USA. His postdoctoral work involved studying the role of lipid peroxidation products and protein carbonylation in alcoholic liver disease. Dr Doorn received his Ph.D. from the University of Michigan, School of Public Health, Toxicology Program. Dr Rochet is an associate professor in the Department of Medicinal Chemistry and Molecular Pharmacology (College of Pharmacy) at Purdue University. Before his arrival at Purdue, Dr Rochet received his PhD degree at the University of Alberta in Biochemistry in 1998 and then worked as a post-doctoral fellow studying mechanisms of alpha-synuclein self-assembly in Parkinson’s disease in the laboratory of Dr. Peter Lansbury at Harvard Medical School. Dr.Rochet’s research group has a long-standing interest in Parkinson’s disease.

Parkinson’s Disease: Pathogenesis and Etiology;

Oxidative Stress and Redox Signalling in the Parkinsonian Brain;

Mitochondrial Dysfunction in Parkinson’s Disease;

Catecholamine Metabolism and the Generation of Reactive Aldehydes;

Dopamine Oxidation and Parkinson's Disease;

GSH and Thiol Redox Signalling;

Nitric Oxide Signalling and  Inflammation in Parkinson’s Disease;

Redox Signalling and Dopaminergic Cell Death/Survival;

Iron Metabolism and Parkinson's Disease; Protein Oxidation, Quality Control and Degradation Pathways;

At the Intersection between Mitochondrial Dysfunction and Lysosomal Autophagy;

Genes, Environment and Aging;

Biomarkers of Oxidative Stress;

Dietary Factors in Parkinson’s Disease;

Antioxidants and Redox-basedTherapeutics