Nitric Oxide and Cancer: Pathogenesis and Therapy (eBook)

Dr. Benjamin Bonavida is a professor at UCLA's David Geffen School of Medicine for the Department of Microbiology, Immunology, & Molecular Genetics. His other appointments include being a member of the Department of Defense Congressionally Directed Medical Research Program, Member of the National Cancer Institute's SPORE Program, member of the International Scientific Advisory Board of the Israel Cancer Research Foundation, to name a few. He's currently a scientific reviewer for several journals and a member of editorial boards including Journal of Clinical Immunology, International Journal of Oncology, and Cancer Biotherapy & Radiopharmaceuticals.

Part I: Molecular Cell Signaling by NO in cancer1. Inflammation-associated Carcinogenesis Involved Interaction Between with iNOS/NO and WNT/beta-cateninQiang Du and David A. Geller 2. NO and Genomic StabilityVasily A. Yakovlev3. Targeting Hyponitroxia in Cancer TherapyBryan Oronsky, Neil Oronsky, Michelle Lybeck, Gary Fanger, Jan Scicinski4. Mechanism of NO-dependent Regulation of Invasion and MetastasisAideen E Ryan, Amy J Burke, Francis J Giles, Francis J Sullivan, Sharon A Glynn5. NO Role in Protumorigenesis and HypoxiaLynne-Marie PostovitPart II: S-nitrosylation and cancer6. Impacts of S-nitrosylation in CancerTysha N. Medeiros, Dana M. Jarigese, Melissa A. Edwards and Mark A. Brown7. S-nitrosylation of Cancer CellsAli Bettaieb, Stéphanie Plenchette, Catherine Paul, Véronique Laurens, Sabrina Romagny, Jean-François Jeannin8. Role of S-nitrosylation in Cancer MetastasisSudjit Luanpitpong and Yon RojanasakulPart III: Modulation of anti-tumor immune responses by NO9. NO Immunity and CancerHermes J. Garbán10. Regulation of Anti-tumor Responses by NOPeter Siesjö11. NO Immune Modulation and Tumor GrowthNaveena B. Janakiram and Chinthalapally V. RaoPart IV: Therapeutics and overcoming resistance 12. Role of NO in Chemo-immune ResistanceBenjamin Bonavida 13. Emerging Role of NO-mediated TherapeuticsCian M. McCrudden and Helen O. McCarthy14. PDT and NOEmilia Della Pietra and Valentina Rapozzi15. Regulation of Cell Death by NOJordi Muntané, Francisco Gallardo-Chamizo, Sheila Pereira, Ángela M. De los Santos, Ángeles Rodríguez-Hernández, Luís M. Marín, Jose M. Álamo, Francisco J Padillo16. Discovery and Development of RRx-001Jan Scicinski, Bryan Oronsky, Shoucheng Ning, Gary R Fanger, Susan J Knox, Mark BednarskiPart V: NO Meditated Alterations in Gene Products 17. Nitric Oxide Coagulation and CancerBenjamin A. Derman, Hau C. Kwaan, Malak Elbatarny, Maha Othman  18. Neutrosphyngomyelinase 2Bei Lei Sun and Bulent Mutus