Cell Therapy for Brain Injury (eBook)

Dr. David C. Hess, MD is currently Chairman and Professor, Department of Neurology, Joint Appointment, Institute of Molecular Medicine and Genetics and Joint Appointment, College of Graduate Studies at Georgia Regents University. He completed his MD at University of Maryland Medical College of Georgia in Baltimore and an internship and residency in Internal Medicine at Allegheny General Hospital in Pittsburgh, before completing an additional residency in Neurology at Georgia Health Sciences University in Augusta. Dr. Hess has authored or co-authored more than 150 papers. This book reflects the intersection between Dr. Hess' clinical interest in stroke and his research interest in stem cells.

Introduction to Cell Therapy in Brain Injury.- Cell Based Therapeutics in Stroke: An Industry Perspective.- Autologous Mesenchymal Stem Cell Therapy in Patients with Stroke.- Treatment of Autologous Bone Marrow Mononuclear Cells for Acute and Subacute Stroke: Cell-Therapy for Acute/Subacute Stroke.- Clinical Development of MultiStem® for Treatment of Injuries and Diseases of the Central Nervous System.- Intra-Arterial Approaches to Stem Cell Therapy for Ischemic Stroke.- Neural Stem Cells in Stroke: Intracerebral Approaches.- The CTX Human Neural Stem Cell Line and the PISCES Stroke Trial.- Induced Pluripotent Stem Cells as a Cell-based Therapeutic in Stroke.- Induced Pluripotent Stem Cell Derived Neural Cell Types In Treatment of Stroke.- Preconditioning and Cell-based Therapeutics.- Tracking of Administered Progenitor Cells in Brain Injury and Stroke by Magnetic Resonance Imaging.- Biomaterials Application in Stem Cell Therapies for Stroke.- A Stem Cell Derived Cell-Free Therapy for Stroke: Moving Conditioned Medium into Clinical Trial.- Pathophysiology of Traumatic Brain Injury: Rationale and Role for Cellular Therapies.- Stem Cell Therapy for Neonatal Hypoxic-Ischemic Brain Injury.- Cell-Based Therapies in Neonatal Stroke.- Issues in Clinical Trial Design in Stem Cell Trials after Stroke.