Proteomics for Biological Discovery
Wiley-Blackwell (an imprint of John Wiley & Sons Ltd) (Verlag)
978-0-471-16005-2 (ISBN)
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Presents a comprehensive and coherent review of the major issues faced in terms of technology development, bioinformatics, strategic approaches, and applications* Chapters offer a rigorous overview with summary of limitations, emerging approaches, questions, and realistic future industry and basic science applications* Discusses higher level integrative aspects, including technical challenges and applications for drug discovery* Accessible to the novice while providing experienced investigators essential information Proteomics for Biological Discovery is an essential resource for students, postdoctoral fellows, and researchers across all fields of biomedical research, including biochemistry, protein chemistry, molecular genetics, cell/developmental biology, and bioinformatics.
TIMOTHY D. VEENSTRA, PhD, is the Director of the Laboratory of Proteomics and Analytical Technologies, National Cancer Institute-Frederick, Frederick, Maryland. JOHN R. YATES III, PhD, is in the Department of Cell Biology, The Scripps Research Institute, La Jolla, California.
Forward. Genomics: Where We Are and Where Are We Going (T. Pawson). PART I: FOUNDATIONS OF PROTEOMICS. 1. Mass Spectrometry: The Foundations of Proteomics (T. Veenstra). 2. Proteomic Analysis by Two-Dimensional Polycrylamide Gel Electrophoresis (J. Celis). 3. Isotope Labeling in Quantitative Proteomics (C. Fenselau). 4. Proteome Analysis of Post-Translational Modifications (T. Veenstra). 5. Technologies for Large Scale Proteomic Tandem Mass Spectrometry (J. Yates). 6. Protein Fractionation Methods for Proteomics (T. Rabilloud). PART II: FUNCTIONAL PROTEOMICS. 7. Protein Localization by Cell Imaging (T. Davis). 8. Characterization of Functional Protein Complexes (C. Robinson). 9. Structural Proteomics by NMR (M. Clore). PART III: NOVEL APPROACHES IN PROTEOMICS. 10. Protein Microarrays (D. Munroe). 11. Microfluidics (C. Lee). 12. Single Cell Proteomics (N. Dovichi). 13. Diagnostic Proteomics (H. Issaq). 14. Automation in Proteomics (T. Veenstra). 15. Bioinformatics (D. Liebler). Index.
Erscheint lt. Verlag | 21.7.2006 |
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Zusatzinfo | Illustrations (some col.) |
Verlagsort | Chicester |
Sprache | englisch |
Maße | 180 x 252 mm |
Gewicht | 634 g |
Themenwelt | Naturwissenschaften ► Biologie |
Naturwissenschaften ► Chemie | |
ISBN-10 | 0-471-16005-9 / 0471160059 |
ISBN-13 | 978-0-471-16005-2 / 9780471160052 |
Zustand | Neuware |
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