Peroxisome Proliferators -

Peroxisome Proliferators

Unique Inducers of Drug-Metabolizing Enzymes

David E. Moody (Herausgeber)

Buch | Hardcover
200 Seiten
1994
Crc Press Inc (Verlag)
978-0-8493-8305-2 (ISBN)
43,60 inkl. MwSt
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Induction of drug (xenobiotic)-metabolizing enzymes is a common biological response to xenobiotics, the mechanisms and consequences of which are important in academic, industrial, and regulatory areas of pharmacology and toxicology. This monograph, for the first time, has brought together researchers who deal specifically with drug-metabolizing enzymes and peroxisome proliferators. It contains an up-to-date review of peroxisome proliferation, with detailed tables on the 100 known peroxisome proliferators and studies on their hepatocarcinogic capacity. It provides current material from 12 different laboratories doing cutting-edge research on the effect of peroxisome proliferators on drug-metabolizing enzymes.The book covers the response of cytochrome P450s, UDP-glucuronosyltransferases, epoxide hydrolases, glutathione S-transferase, DT-diaphorase, and other enzymes.

Peroxisome Proliferation: An Overview, D.E. Moody
Induction of Cytochromes P450 by Peroxisome Proliferators, G.G. Gibson, M.J. Diaz, E. Chinje, and P. Kentish
Effect of Peroxisome Proliferators on Microsomal P450 Reactions, R.T. Okita
Inhibition of Cytochrome P450 4A Enzymes and Peroxisome Proliferation, P. Ortez de Montellano, R.M. Kaikaus, W.K. Chan, Z. Sui, and N.M. Bass
Peroxisome Proliferator Activated Receptor-Mediated Induction of P450 4A, E.F. Johnson, M.-H. Hsu, and C.N.A. Palmer
UDP-Glucuronosyltransferases and Peroxisome Proliferators, J. Magdalou, S. Fournel-Gigleux, H. Goudonnet, M. Pritchard, and G. Siest
The Response of Soluble Epoxide Hydrolase and Other Hydrolytic Enzymes to Peroxisome Proliferators, D.F. Grant, D.E. Moody, J. Beetham, D.H. Storms, M.F. Moghaddam, B. Borhan, F. Pinot, B. Winder, and B.D. Hammock
Peroxisome Proliferation and the Subcellular Localization of Soluble Epoxide Hydrolase: Role of Peroxisomal Targeting Sequences, S.S. Gill, D.F. Grant, J.K. Beetham, and C. Chang
Responses of Epoxide Hydrolases, Glutathoine S-Transferase, DT-Diaphorase and Catalase in Mouse Liver to Treatment with Peroxisome Proliferators, J.W. DePierre, A.-K. Sohlenius, A.M. Eriksson, M. Soderstrom, H. Permadi, K. Andersson, C. Sundberg, and B. Lundgren
Anti-Oxidant Activity Modulation by Peroxisome Proliferators, J.D. Budroe and G.M. Williams
Induction of Drug-Metabolizing Enzymes by Short/Intermediate-Term Exposure to Peroxisome Proliferators-A Synopsis, F. Oesch and M. Arand
Drug Metabolizing Enzymes as Part of the Unique Phenotypic Properties of Peroxisome Proliferator-Induced Liver Tumors, M.S. Rao and J.K. Reddy).

Erscheint lt. Verlag 12.7.1994
Reihe/Serie Handbooks in Pharmacology and Toxicology
Co-Autor Bruce D. Hammock, Richard T. Okita, Eric F. Johnson
Mitarbeit Herausgeber (Serie): Mannfred A. Hollinger
Zusatzinfo 21 Tables, black and white; 9 Halftones, black and white; 9 Illustrations, black and white
Verlagsort Bosa Roca
Sprache englisch
Maße 178 x 254 mm
Gewicht 589 g
Themenwelt Studium 2. Studienabschnitt (Klinik) Pharmakologie / Toxikologie
Naturwissenschaften Biologie Biochemie
ISBN-10 0-8493-8305-6 / 0849383056
ISBN-13 978-0-8493-8305-2 / 9780849383052
Zustand Neuware
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