Transcriptomics in Health and Disease (eBook)

Part 1: Basic Principles of the Transcriptome and its Analysis.- What is the Transcriptome and how it is Evaluated?.- Transcriptome Analysis Throughout RNA-seq.- Identification of Biomarkers and Expression Signatures.- Methods for Gene Co-expression Network Visualization and Analysis.- Posttranscriptional Control During Stem Cells Differentiation.- Transcriptome Analysis During Normal Human Mesenchymal Stem Cell Differentiation.- Part II: Transcriptome in Disease.- Thymus Gene Co-expression Networks: A comparative study in children with and without down syndrome.- Transcriptome Profiling in Autoimmune Diseases.- Expression of DNA Repair and Response to Oxidative Stress Genes in Diabetes Mellitus.- MicroRNAs in Cancer.- Transcriptome Profiling in Chronic Inflammatory Diseases of the Musculoskeletal System.- Transcriptome Profiling in Experimental Inflammatory Arthritis.- Transcriptome in Human Mycoses.- Transcriptomics of the Host-pathogen Interaction in Paracoccidioidomycosis.- Dissecting Tuberculosis through Transcriptomic Studies.- Understanding chagas Disease by Genome and Transcriptome Exploration.- Expression Tests in Actual Clinical Practice: How medically useful is the transcriptome?.- Conclusions.- Index.