RGS Protein Physiology and Pathophysiology

Dr. Fisher is a 1983 graduate of Iowa State University (Ph.D.), who performed post-doctoral research at the University of Texas Health Science Center, San Antonio, before joining the faculty in Pharmacology at the University of Iowa in 1987. He was promoted to associate professor in 1993 and to professor in 2004. He has a secondary appointment in the Department of Internal Medicine and is a member of the Molecular and Cellular Biology interdisciplinary graduate program, the Holden Cancer Center, the Medical Scientist Training Program, and the Gene Therapy Center. His research focuses on the biology and signaling of RGS proteins and G proteins. He has served on numerous NIH study sections and his funding includes an R01 to study novel actions of RGS6 in tumor suppression and DNA damage signaling.

Introduction: G Protein-coupled Receptors and RGS Proteins
Adele Stewart and Rory A. Fisher
RGS-insensitive G Proteins as in vivo Probes of RGS Function
Richard R. Neubig
RGS Protein Regulation of Phototransduction 
Ching-Kang Jason Chen
Role of Regulators of G Protein Signaling (RGS) Proteins in Bone Physiology and Pathophysiology
Joel Jules, Shuying Yang, Wei Chen and Yi-Ping Li
Regulator of G Protein Signaling 2: A Versatile Regulator of Vascular Function
Patrick Osei-Owusu and Kendall J. Blumer
Keeping the Balance Right: Regulator of G Protein Signaling 5 in Vascular Physiology and Pathology
Ruth Ganss
Two for the Price of One: G Protein-Dependent and -Independent Functions of RGS6 in vivo
Adele Stewart, Biswanath Maity and Rory A. Fisher
Physiology of RGS10 in Neurons and Immune Cells
Jae-Kyung Lee and Malú G. Tansey
Regulator of G Protein Signaling 14 (RGS14): A Molecular Brake for Synaptic Plasticity Linked to Learning and Memory
Paul R. Evans, Serena M. Dudek and John R. Hepler