Yeast Functional Genomics and Proteomics

Comparative Genome Hybridization on Tiling Microarrays to Detect Aneuploidies in Yeast.- Identification of Transcription Factor Targets by Phenotypic Activation and Microarray Expression Profiling in Yeast.- SGAM: An Array-Based Approach for High-Resolution Genetic Mapping in Saccharomyces cerevisiae.- Reporter-Based Synthetic Genetic Array Analysis: A Functional Genomics Approach for Investigating the Cell Cycle in Saccharomyces cerevisiae.- The Fidgety Yeast: Focus on High-Resolution Live Yeast Cell Microscopy.- A Genomic Approach to Yeast Chronological Aging.- Chemogenomic Approaches to Elucidation of Gene Function and Genetic Pathways.- Identification of Inhibitors of Chromatin Modifying Enzymes Using the Yeast Phenotypic Screens.- Exploiting Yeast Genetics to Inform Therapeutic Strategies for Huntington’s Disease.- Global Proteomic Analysis of Saccharomyces cerevisiae Identifies Molecular Pathways of Histone Modifications.- Systematic Characterization of the Protein Interaction Network and Protein Complexes in Saccharomyces cerevisiae Using Tandem Affinity Purification and Mass Spectrometry.- Protein Microarrays.- Analysis of Protein–Protein Interactions Using Array-Based Yeast Two-Hybrid Screens.- Analysis of Membrane Protein Complexes Using the Split-Ubiquitin Membrane Yeast Two-Hybrid System.- Computational Analysis of the Yeast Proteome: Understanding and Exploiting Functional Specificity in Genomic Data.

From the reviews:

“This volume takes a snapshot of the questions which can be asked with a genome … . A major value of this book may be in helping to overcome the fear factor. Most of the approaches are feasible in a moderately resourced laboratory, and as the tools for S. cerevisiae spread to other organisms, so will the potential usefulness of this collection.” (John Armstrong, Microbiology Today, January, 2010)