Molecular Genetics of Mycobacteria

IntroductionMycobacterial Genetics: A Historical Perspective Section 1: Structure of Mycobacterial Genomes1. The Genome Structure of M. tuberculosis H37 Rv2. The Genome Structure of M. tuberculosis CSU No.933. Population Structure of M. tuberculosis Strains Section 2: Mechanisms of Genetic Exchange4. Mycobacteriophage Genetics5. Plasmids6. Transposons7. Transduction in the Mycobacteria8. General Recombination9. Mycobacterial Conjugation Section 3: Mycobacterial Gene Expression10. Determinants of Mycobacterial Gene Expression11. Gene Expression: Reporter Gene Technologies12. Gene Expression: Mechanisms of Gene Regulation Section 4: Metabolism13. DNA Replication14. Genetics of Mycobacterial Metabolism15. Genetics of Drug Resistance16. Genetics of Cell wall Biosynthesis17. The Heat-Shock Response Section 5: Genetic Strategies18. Mutants and Mutagenesis19. Gene Replacement in Mycobacteria20. Genetics of Mycobacterial Virulence21. Genetic Strategies for Vaccine Development22. Genetic Approaches to Drug Development23. Structural Approaches to Understanding the Mycobacteria24. Genetics of Mycobacterial Persistence