Modern Microbial Genetics

Uldis N. Streips was born in Riga, Latvia and emigrated with his family to the United States in 1951. He received a BS in Chemistry and Biology from Valparaiso University, Valparaiso IN in 1964 and a Ph.D. in Microbiology from Northwestern University in 1969. He did postdoctorate research at Scripps Clinic and Research Foundation, LaJolla, CA, and the University of Rochester School of Medicine, Rochester NY. He has been on the faculty of the University of Louisville, School of Medicine since 1972. His principal research area is microbial genetics and physiology. He has 65 peer-reviewed publications and books and chapters. He has received 14 teaching awards at the University of Louisville. Streips has mentored 15 Ph.D. and 2 M.S. students. He is a Foreign Member of the Latvian Academy of Sciences and the chief officer of the annual Wind River Conference on Prokaryotic Biology. He has run summer workshops for high school teachers for the last 14 years.

Preface. Preface to the First Edition. Introduction. Contributors. SECTION I: DNA METABOLISM. Prokaryotic DNA Replication (W. Firshein). DNA Repair Mechanisms and Mutagenesis (R. Yasbin). Gene Expression and Its Regulation (J. Helmann). Bacteriophage Genetics (B. Guttan & E. Kutter). Bacteriophage and Its Relatives (R. Hendrix). Single-Stranded DNA Phages (J. LeClerc). Restriction-Modification Systems (R. Blumenthal & X. Cheng). Recombination (S. Levene & K. Huffman). Molecular Applications (T. Geoghegan). SECTION II: GENETIC RESPONSE. Genetics of Quorum Sensing Circuitry in Pseudomonas aeruginosa: Implications for Control of Pathogenesis, Biofilm Formation and Antibiotic/Biocide Resistance (D. Hassett, et al.). Endospore Formation in Bacillus subtilis: An Example of Cell Differentiation by a Bacterium (C. Moran). Stress Shock (U. Streips). Genetic Tools for Dissecting Motility and Development of Myxococcus xanthus (P. Hartzell). Agrobacterium Genetics (W. Ream). Two-Component Regulation (K. Bayles & D. Fujimoto). Molecular Mechanisms of Quorum Sensing (C. Fuqua & M. Parsek). SECTION III: GENETIC EXCHANGE. Bacterial Transposons--An Increasingly Diverse Group of Elements (G. Whittle & A. Salyers). Transformation (U. Streips). Conjugation (R. Porter). The Subcellular Entities a.k.a. Plasmids (M. Perlin). Transduction in Gram-Negative Bacteria (G. Weinstock). Genetic Approaches in Bacteria with No Natural Genetic Systems (C. Haller & T. DiChristina). Index.