Poly(ADP-Ribosyl)ation - Alexander Bürkle

Poly(ADP-Ribosyl)ation

Buch | Softcover
246 Seiten
2014
Springer-Verlag New York Inc.
978-1-4899-8803-4 (ISBN)
160,49 inkl. MwSt
Poly(ADP-Ribosyl)ation comprises 19 chapters written by leading international experts in the field and is richly illustrated. Extensive bibliography is given in each chapter.

Enzymes in Poly(ADP-Ribose) Metabolism.- PARP-2: Structure-Function Relationship.- Targeting the Poly (ADP-Ribose) Glycohydrolase (PARG) Gene in Mammals.- DNA Damage Signaling through Poly(ADP-Ribose).- Roles of Poly(ADP-Ribose) Metabolism in the Regulation of Centrosome Duplication and in the Maintenance of Neuronal Integrity.- Functional Interactions of PARP-1 with p53.- Dynamic Interaction between PARP-1, PCNA and p21waf1/cip1.- PARP-1 as Novel Coactivator of NF-?B in Inflammatory Disorders.- PARP and Epigenetic Regulation.- PARP and the Release of Apoptosis-Inducing Factor from Mitochondria.- Genome Degradation by DNAS1L3 Endonuclease.- NAD: Metabolism and Regulatory Functions.- PARP-1 and the Shape of Cell Death.- Poly(ADP-Ribose) Polymerase (PARP) and Excitotoxicity.- Poly(ADP-Ribose) Polymerase and Ischemia-Reperfusion Injury.- Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Inflammation and Circulatory Shock.- Role of Poly-ADP-Ribosylation in Cancer Development.- PARP Inhibitors and Cancer Therapy.- Poly(ADP-Ribosyl)ation and Aging.

Erscheint lt. Verlag 4.12.2014
Reihe/Serie Molecular Biology Intelligence Unit
Zusatzinfo XVII, 246 p.
Verlagsort New York
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Studium 2. Studienabschnitt (Klinik) Humangenetik
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
ISBN-10 1-4899-8803-3 / 1489988033
ISBN-13 978-1-4899-8803-4 / 9781489988034
Zustand Neuware
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