Prions and Diseases

Transmissible Spongiform Encephalopathy: from the High Middle Ages to Daniel Carlton Gajdusek.- The Rich Chemistry of the Copper and Zinc Sites in Cellular Prion Protein.- Role of Cellular Prion Protein in the Amyloid-ß Oligomer Pathophysiology of Alzheimer’s Disease.- Cellular Prion Protein and Cancers.- Insoluble Cellular Prion Protein.- Protein Misfolding Cyclic Amplification.- Cofactor Involvement in Prion Propagation.- Prion Protein Conversion and Lipids.- New Perspectives on Prion Conversion: Introducing a Mechanism of Deformed Templating.- Infectious and Pathogenic Forms of Prion Protein.- Cellular Mechanisms of Propagation and Clearance.- Molecular Mechanisms Encoding Quantitative and Qualitative Traits of Prion Strains.- Modeling the Cell Biology of Prions.- Prion Strain Interference.- Introduction to Yeast and Fungal Prions.- Yeast Prions are Pathogenic, in-register Parallel Amyloids.