Evolution of Genetics (eBook)
226 Seiten
Elsevier Science (Verlag)
978-1-4832-6358-8 (ISBN)
The book opens with a chapter on the legacy of classical genetics. This is followed by separate chapters on the use of microorganisms in molecular genetics; the structure and replication of genetic material; mutation and recombination of genetic material; the heterocatalytic function of genetic material; and concludes with a discussion of the future of genetics.
Undergraduates considering a career of teaching or research in biology, students who are embarking on graduate studies in biology, professional biologists working in fields other than genetics but interested in current research on heredity, and laymen who have had some education in biology and have a continued interest in biological science may find something useful in this book.
The Evolution of Genetics provides a review of the development of genetics. It is not intended as a history of the science of heredity. By a brief and general survey, however, it seeks to show the connections of past to present research, and of current discoveries to future investigations. The book opens with a chapter on the legacy of classical genetics. This is followed by separate chapters on the use of microorganisms in molecular genetics; the structure and replication of genetic material; mutation and recombination of genetic material; the heterocatalytic function of genetic material; and concludes with a discussion of the future of genetics. Undergraduates considering a career of teaching or research in biology, students who are embarking on graduate studies in biology, professional biologists working in fields other than genetics but interested in current research on heredity, and laymen who have had some education in biology and have a continued interest in biological science may find something useful in this book.
Front Cover 1
The Evolution of Genetics 4
Copyright Page 5
Table of Contents 10
PREFACE 8
CHAPTER 1. THE LEGACY OF CLASSICAL GENETICS 12
The Concept of the Gene 15
Interaction of Alleles and of Nonallelic Genes 21
The Relation of Gene to Character 23
Localization of the Gene on the Chromosome 26
The Universality of Genetic Theory 39
A Genetic Theory of Evolution 40
The Role of the Cytoplasm in Heredity 41
The Questions Raised by Classical Genetics 43
CHAPTER 2. THE USE OF MICROORGANISMS IN MOLECULAR GENETICS 44
Molecular Specificity and Organization within the Cell 45
Mutation and Adaptation in Microorganisms 49
The Mode of Genetic Recombination in Higher Organisms 54
Modes of Genetic Recombination in Bacteria: Transformation 60
Modes of Genetic Recombination in Bacteria: Lysogeny and Lysogenic Conversion Bacteriophage Recombination
Modes of Genetic Recombination in Bacteria: Conjugation 74
Modes of Genetic Recombination in Bacteria: Transduction 83
Modes of Genetic Recombination in Bacteria: Sexduction 88
CHAPTER 3. THE STRUCTURE AND REPLICATION OF GENETIC MATERIAL 91
Selective Systems for Detecting Rare Mutations and Recombinations 93
The Divisibility of the Gene 114
The Structure of DNA 120
The Replication of DNA 130
The in Vitro Synthesis of DNA 132
CHAPTER 4. MUTATION AND RECOMBINATION OF GENETIC MATERIAL 138
Theoretical Basis of Mutagenesis 139
The Mutagenic Action of Base Analogues 143
The Chemical Alteration of Bases in Vitro 148
Mutations by the Deletion or Addition of Nucleotides to the DNA Molecule 150
Recombination at the Molecular Level 156
The Mechanism of Molecular Recombination 159
The Anomalies of Molecular Recombination 167
The Molecular Model of Mutation and Recombination: a Summary 172
CHAPTER 5. THE HETEROCATALYTIC FUNCTION OF GENETIC MATERIAL 174
The Genetic Code 174
The Indirect Action of the Genetic Code: The Role of RNA 183
Experimental Verification of the Messenger Model of Protein Synthesis 187
Colinearity of the Structural Gene with the Polypeptide It Determines 191
Proteins as Aggregates and the Phenomenon of Complementation 194
Intergenic Suppression 197
Regulator Genes 203
CHAPTER 6. THE FUTURE OF GENETICS: TODAY'S UNSOLVED PROBLEMS 207
The Genes and the Cytoplasm in Morphogenesis 209
Behavior, an Aspect of Development 213
DNA and the Chromosome 214
Recombination, Crossing-over, and Chromosomal Rearrangements 220
Mutation, Chromosomal Rearrangements, and Evolution 224
Concluding Argument 230
REFERENCES 231
INDEX 236
| Erscheint lt. Verlag | 11.9.2013 |
|---|---|
| Sprache | englisch |
| Themenwelt | Naturwissenschaften ► Biologie ► Evolution |
| Technik | |
| ISBN-10 | 1-4832-6358-4 / 1483263584 |
| ISBN-13 | 978-1-4832-6358-8 / 9781483263588 |
| Haben Sie eine Frage zum Produkt? |
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