Advances in Oxytocin Research -

Advances in Oxytocin Research (eBook)

Proceedings of a Symposium Held on 1st May 1964 Under the Auspices of the Blair-Bell Research Society at the Royal College of Obstetricians and Gynaecologists, Sussex Place, Regent's Park, London, England

J. H. M. Pinkerton (Herausgeber)

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2013 | 1. Auflage
162 Seiten
Elsevier Science (Verlag)
978-1-4831-5650-7 (ISBN)
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Advances in Oxytocin Research documents the proceedings of a symposium held by the Blair-Bell Research Society at the Royal College of Obstetricians and Gynecologists, London, England, on 1st May 1964. Oxytocin was chosen as the subject of the symposium due to recent important work on its physiology and pharmacology, and the availability of a new method of administering the drug for the induction of labor in women after extensive study in America, Europe, and Great Britain. The volume contains papers presented by during the two sessions held during the symposium. The first session on the physiology and pharmacology of oxytocin includes studies on the circulatory effects of oxytocin, release of oxytocin during parturition, and the release of oxytocin in domestic animals. The second session on clinical applications includes papers on the endocrine control of labour, clinical trials of buccal oxytocin, and tge oxytocin sensitivity test. Also included are the opening remarks by Sir Arthur Bell, President of the Blair-Bell Society and the Chairman's Introduction at the beginning of each session.
Advances in Oxytocin Research documents the proceedings of a symposium held by the Blair-Bell Research Society at the Royal College of Obstetricians and Gynecologists, London, England, on 1st May 1964. Oxytocin was chosen as the subject of the symposium due to recent important work on its physiology and pharmacology, and the availability of a new method of administering the drug for the induction of labor in women after extensive study in America, Europe, and Great Britain. The volume contains papers presented by during the two sessions held during the symposium. The first session on the physiology and pharmacology of oxytocin includes studies on the circulatory effects of oxytocin, release of oxytocin during parturition, and the release of oxytocin in domestic animals. The second session on clinical applications includes papers on the endocrine control of labour, clinical trials of buccal oxytocin, and tge oxytocin sensitivity test. Also included are the opening remarks by Sir Arthur Bell, President of the Blair-Bell Society and the Chairman's Introduction at the beginning of each session.

Front Cover 1
Advances in Oxytocin Research 4
Copyright Page 5
Table of Contents 6
PREFACE 8
LIST OF CONTRIBUTORS 10
THE BLAIR-BELL RESEARCH SOCIETY 13
PART I: PHYSIOLOGY AND PHARMACOLOGY 14
CHAPTER 1. OPENING REMARKS BY THE PRESIDENT OF THE BLAIR-BELL SOCIETY 16
CHAPTER 2. CHAIRMAN'S INTRODUCTION 18
REFERENCES 22
CHAPTER 3. SOME OBSERVATIONS ON THE CIRCULATORY EFFECTS OF OXYTOCIN, VASOPRESSIN AND SIMILAR POLYPEPTIDES 24
Method 28
Results 32
Discussion 41
Summary 44
REFERENCES 45
DISCUSSION 47
CHAPTER 4. OXYTOCIN LEVELS IN THE BLOOD OF RUMINANTS WITH SPECIAL REFERENCE TO THE MILKING STIMULUS 50
1. Introduction 50
2. Cows during Machine Milking 54
3. Goats during Hand Milking 56
4. Goats during Parturition 57
5. Discussion 57
Acknowledgements 61
REFERENCES 62
CHAPTER 5. THE RELEASE OF OXYTOCIN DURING PARTURITION 64
Introduction 64
Experimental Observations 66
Methods 68
Results 73
Conclusions 83
Acknowledgements 84
REFERENCES 85
DISCUSSION 86
CHAPTER 6. STUDIES ON THE RELEASE OF OXYTOCIN IN DOMESTIC ANIMALS 90
REFERENCES 95
DISCUSSION 96
PART II: CLINICAL APPLICATIONS 98
CHAPTER 7. CHAIRMAN'S INTRODUCTION 100
CHAPTER 8. SOME ASPECTS OF THE ENDOCRINE CONTROL OF LABOUR 102
REFERENCES 116
CHAPTER 9. CLINICAL TRIALS OF BUCCAL OXYTOCIN 118
1. Background 118
2. Method of Administration 119
British and Scandinavian Trials 120
The Effect of Ruptured Membranes and Complications of Delivery (Table 2) 123
Complications of Treatment 127
Summary 128
REFERENCES 129
CHAPTER 10. THE OXYTOCIN SENSITIVITY TEST: A Review of Ten Years' Results 130
Summary 137
Acknowledgements 137
REFERENCES 137
CHAPTER 11. THE OXYTOCIN SENSITIVITY TEST 140
Technique 140
Results 141
Discussion 144
Summary 147
REFERENCES 148
DISCUSSION 148
CHAPTER 12. CHAIRMAN'S CLOSING REMARKS 162
CHAPTER 13. CLOSING REMARKS BY THE PRESIDENT OF THE ROYAL COLLEGE OF OBSTETRICIANS AND GYNAECOLOGISTS 164

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