Kidney (eBook)

Front Cover 1
The Kidney: Morphology, Biochemistry, Physiology 4
Copyright Page 5
Table of Contents 10
List of Contributors 6
Preface 8
Contents of other Volumes 14
CHAPTER 1. EXPLANTS OF EMBRYONIC KIDNEY: TECHNIQUES AND APPLICATIONS 16
Introduction 17
I. Explantation Techniques 17
II. The Differentiation of Kidney Primordia by Culture Techniques 24
III. Application of the Techniques to Organotype Culture of Tumors 59
IV. Cultures of Embryonic Organs Associated with Mesonephros 88
REFERENCES 92
CHAPTER 2. EXPERIMENTAL GLOMERULAR DISEASES 98
I. Introduction 99
II. Hypersensitivity Glomerular Diseases 102
III. Glomerular Abnormalities due to Freund's Adjuvant 145
IV. Naturally Occurring Glomerular Disease 149
V. Glomerular Disease due to Colloidal Materials 153
VI. Glomerular Alterations Resulting from Intravascular Coagulation 158
VIL Glomerular Lesions Produced by Microorganisms or Products of Microorganisms 165
VIII. Glomerular Abnormalities Produced by Radiation 170
IX. Glomerular Abnormalities Produced by Cortisone 173
X. Glomerular Disease due to Renal Vein Occlusion 174
XI. Glomerular Lesions in Experimental Diabetes 175
XII. Glomerular Lesions due to Miscellaneous Toxins 176
XIII. Renal Amyloidosis 182
XIV. Summary of Pathogenetic Mechanisms in Experimental Glomerulonephritis 183
XV. Possible Relationship of Experimental Models to Human Glomerular Diseases 185
REFERENCES 193
CHAPTER 3. EXPERIMENTAL KIDNEY TUMORS 214
Introduction 214
I. Spontaneous Kidney Tumors in Animals 215
II. Kidney Tumors Caused by Virus 227
III. Kidney Tumors Caused by Chemical Agents 243
IV. Kidney Tumors Induced by Hormones in Hamsters 254
V. Radiation-Induced Kidney Tumors 263
VI. Conclusion 268
REFERENCES 270
CHAPTER 4. EXPERIMENTAL PYELONEPHRITIS 284
I. Scope of This Review 284
II. Pathogenesis of Pyelonephritis 286
III. The Renal Lesion in Experimental Pyelonephritis 322
IV. Pyelonephritis and Hypertension 356
V. Summary 359
ACKNOWLEDGMENT 360
REFERENCES 360
CHAPTER 5. ERYTHROPOIETIN 378
I. Definition 378
II. Historical Summary 379
III. Methods of Assay of Erythropoietin 380
IV. Purification and Nature of Erythropoietin 382
V. Erythropoietin Production and Regulation of Erythropoiesis 384
VI. Relation between Endocrine Glands and Erythropoietin 389
VII. The Mechanism of Action of Erythropoietin 391
VIII. Metabolism of Erythropoietin 394
IX. Site of Production of Erythropoietin 395
X. Clinical Aspects 400
REFERENCES 405
CHAPTER 6. EXPERIMENTAL RENAL TOXICITY 416
I. Introduction 416
II. Toxic Changes of the Kidney 425
REFERENCES 476
CHAPTER 7. KIDNEY AND VIRUSES 492
I. Introduction 492
II. Viruria 493
III. Inclusion-Bearing Cells in Urinary Sediment and Their Significance 496
IV. Nephropathy Accompanying Known or Suspected Virus Infections 497
V. Viruses and Renal Transplantation 500
VI. General Comments on Viruses and Kidney Disease 500
VII. Susceptibility of Kidney Cells to Virus in Vitro and in Vivo 502
VIII. Viruses and Cancer of the Kidney 503
REFERENCES 503
AUTHOR INDEX 508
SUBJECT INDEX 533