Bone, Volume IX

This text is one of a series of nine volumes devoted to providing up-to-date, comprehensive, and authoritative coverage of all aspects of bone. This volume describes the morphogenesis and differentiation of bone.

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Volume 9 provides an authoritative overview of mechanisms controlling differentiation and morphogenesis of bone, especially in craniofacial mesenchyme. The important role played by homeobox genes in patterning the skeleton is reviewed by two major workers in this rapidly moving field. How membrane bones repair themselves is discussed from both basic science and clinical perspectives. Finally, a chapter on mechanisms underlying the developmental integration of skeleton and muscles provides an analysis important for future advances in this field.