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Molecular Mechanisms Underpinning the Development of Obesity

Clévio Nóbrega, Raquel Rodriguez-López (Herausgeber)

Buch | Hardcover

XII, 194 Seiten

2014 | 2014
Springer International Publishing (Verlag)
978-3-319-12765-1 (ISBN)

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Obesity is a multi-factorial disease, in which an excess of accumulated body fat can reach levels capable of affecting health. It results from an interplay between environmental factors, eating behavior, genes, epigenetics, and neuronal stimuli. The main aim of this book is to provide a state-of-the-art revision about the molecular mechanisms underpinning the development of obesity, reviewing the current knowledge in areas like monogenic and polygenic obesity forms, but also providing an updated view of the emerging knowledge about epigenetics, nutrigenomics, and neuronal aspects that also contribute to obesity.

Challenges in understanding development of obesity.- Monogenic forms of obesity.- Heterogeneous obesity syndromes: new strategies for diagnosis.- Genetic contribution: common forms of obesity.- The role of the GWAS identified FTO locus in regulating body size and composition.- Neural vulnerability factors that increase risk for weight gain: prevention and treatment implications.- Molecular mechanisms involved in the regulation of food intake.- Epigenetics of human obesity: a link between genetics and nutrition.- MicroRNAs in obesity and metabolism.- Obesity study: animal models.- From Homo obesus to Homo diabesus: neuroadipology insight.- Obesity and type 2 diabetes.

Erscheint lt. Verlag	30.12.2014
Zusatzinfo	XII, 194 p. 24 illus., 15 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	479 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete
	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Zellbiologie
Schlagworte	Development • Diabetes • Genetics • GWAS • Molecular mechanisms • Obesity
ISBN-10	3-319-12765-9 / 3319127659
ISBN-13	978-3-319-12765-1 / 9783319127651
Zustand	Neuware