Biological Effects of Low Level Exposures Dose-Response Relationships

Edward J. Calabrese

Historical, Philosophical, Conceptual Foundations of BELLE Research: Includes four chapters of introductory material. Biological Effects of Low Level Exposure to Chemicals: Nonmonotonic Dose-Response Relationships in Toxicological Studies. Biostatistical Approaches to Low Level Exposures. Responses in Humans to Low Level Exposures. Cellular and Molecular Foundations of Hormetic Mechanisms. Modulation of Toxicity by Diet: Implications for Response at Low Level Exposures. Biological Effects of Low Level Exposure to Radiation: What Can be Learned from Epidemiologic Studies of Persons Exposed to Low Doses of Radiation? Positive Health Effects of Low Level Radiation in Human Populations. Test of the Linear-No Threshold Theory of Radiation Carcinogenesis. Bayesian Estimation of Incidence Change-Points in Low Dose Experimental and Epidemiologic Studies. Radiation-Induced Carcinogenesis: Paradigm Considerations. Stress Proteins and Radiation. Adaptive Responses After Exposure to Low Dose Radiation. BELLE Conference Perspectives and Summary: Synopsis of the BELLE Conference on Chemicals and Radiation. New Perspectives on Dose-Response Relationships and Low Level Exposures. BELLE Conference: A Summary.
Appendix. List of Acronyms and Abbreviations. List of Contributors. Index.