Biochemical Roles of Eukaryotic Cell Surface Macromolecules -

Biochemical Roles of Eukaryotic Cell Surface Macromolecules

Buch | Hardcover
IX, 411 Seiten
2014 | 2015
Springer International Publishing (Verlag)
978-3-319-11279-4 (ISBN)
213,99 inkl. MwSt
Consists of critical reviews and original research papers from the 2014 International Symposium on the "Biochemical Role of Eukaryotic Cell Surface Macromolecules". Topics covered include: · neurochemical and biochemical analysis of cell surface glycoconjugates · membrane skeletal organization · GPCRs and other receptors · biophysical approaches to study membrane interactions · glycoconjugate metabolism · dysregulation · molecular mechanisms involved in cell-cell and cell-matrix interaction · glycans in infectious and neurological diseases · cancer and glycosyltransferases as drug targets.

Human-Specific Evolutionary Changes in the Biology of Siglecs.- Structural Changes of GPI Anchor After Its Attachment to Proteins : Functional Significance.- Novel Insights In Membrane Biology Utilizing Fluorescence Recovery After Photobleaching.- Defects in Erythrocyte Membrane Skeletal Architecture.- Membrane Rafts in the Erythrocyte Membrane: A Novel Role of MPP1p55.- Immuno-Modulatory Role of Porins: Host Immune Responses, Signalling Mechanisms and Vaccine Potential.- Vibrio cholerae Cytolysin: Structure-Function Mechanism of an Atypical beta-barrel Pore-Forming Toxin.- New vis-tas in Lactosylceramide Research.- Plasma Membrane-Associated Sialidase Confers Cancer Initiation, Promotion and Progression.- A Signal with a Difference: The Role of GPI Anchor Signal Sequence in Dictating Conformation and Function of the Als5 Adhesin in Candida albicans.- Novel Chondroitin Sulfate Oligosaccharide Motifs as Biomarkers: Insights Into Their Involvement in Brain Development.- Role of Hyaluronidases in the Catabolism of Chondroitin Sulfate.- Pattern Recognition in Legume Lectins to Extrapolate Amino Acid Variability to Sugar Specificity.- Conformational Dynamics of Oligosaccharides Characterized by Paramagnetism-Assisted NMR Spectroscopy in Conjunction with Molecular Dynamics Simulation.- Characterization of Cholesterol Crystalline Domains in Model and Biological Membranes Using X-Ray Diffraction.- Role of Lipid-Mediated Effects in beta2-Adrenergic Receptor Dimerization.- Effect of Temperature on the Phase Behaviour of Fully Saturated DAPC Lipid Bilayer: A Comparative Molecular Dynamics Simulation Study.- Biophysical Characterization of the Interaction of O-acylcholines with the Major Bovine Seminal Plasma Protein, PDC-109.- Crystal Structure of Apo and Ligand Bound Vibrio cholerae Ribokinase (Vc-RK): Role of Monovalent Cation Induced Activation and Structural Flexibility in Sugar Phosphorylation.- Synthetic Glycolipids and (p)ppGpp Analogs:Development of Inhibitors for Mycobacterial Growth, Biofilm and Stringent Response.- Regulations of Glycolipid : Glycosyltransferase (GSL: GLTs) Genes Involved in SA-LeX and Related GSLs Biosysthesis in Carcinoma Cells by Biosimilar Apoptotic Agents : Potential Anticancer Drugs.- N-acetylglucosaminyl 1-phosphate Transferase: An Excellent Target for Developing New Generation Breast Cancer Therapeutic.- Involvement of Vascular Endothelial Growth Factor in Serotonin 1A Receptor-Mediated Neuroproliferation in Neonatal Mouse Hippcampus.- Structural Heterogeneity of Glycoform of Alpha-1 Acid Glycoprotein in Alcoholic Cirrhosis Patients.

Erscheint lt. Verlag 3.12.2014
Reihe/Serie Advances in Experimental Medicine and Biology
Zusatzinfo IX, 411 p. 127 illus., 72 illus. in color.
Verlagsort Cham
Sprache englisch
Maße 155 x 235 mm
Gewicht 848 g
Themenwelt Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Zellbiologie
Naturwissenschaften Chemie Organische Chemie
Schlagworte carbohydrate chemistry • cell surface • glycoconjugates • Membrane • Membrane Skeleton • receptors
ISBN-10 3-319-11279-1 / 3319112791
ISBN-13 978-3-319-11279-4 / 9783319112794
Zustand Neuware
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