Micro- and Nanoengineering of the Cell Surface -

Micro- and Nanoengineering of the Cell Surface (eBook)

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2014 | 1. Auflage
400 Seiten
Elsevier Science (Verlag)
978-1-4557-3155-8 (ISBN)
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Micro- and Nanoengineering of the Cell Surface explores the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes. The book is accessible for readers across industry, academia, and in clinical settings in multiple disciplines, including materials science, engineering, chemistry, biology, and medicine. Written by leaders in the field, it covers numerous cell surface engineering methods along with their current and potential applications in cell therapy, tissue engineering, biosensing, and diagnosis.

The interface of chemistry, materials science, and biology presents many opportunities for developing innovative tools to diagnose and treat various diseases. However, cell surface engineering using chemistry and materials science approaches is a new and diverse field. This book provides a full coverage of the subject, introducing the fundamentals of cell membrane biology before exploring the key application areas.


  • Demystifies the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes
  • Provides a toolkit of micro- and nanoengineering approaches to the manipulation of the cell surface
  • Unlocks the potential of cell surface manipulation for a range of new applications in the fields of in vitro research, cell therapy, tissue engineering, biosensing, and diagnostics

Micro- and Nanoengineering of the Cell Surface explores the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes. The book is accessible for readers across industry, academia, and in clinical settings in multiple disciplines, including materials science, engineering, chemistry, biology, and medicine. Written by leaders in the field, it covers numerous cell surface engineering methods along with their current and potential applications in cell therapy, tissue engineering, biosensing, and diagnosis. The interface of chemistry, materials science, and biology presents many opportunities for developing innovative tools to diagnose and treat various diseases. However, cell surface engineering using chemistry and materials science approaches is a new and diverse field. This book provides a full coverage of the subject, introducing the fundamentals of cell membrane biology before exploring the key application areas. Demystifies the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes Provides a toolkit of micro- and nanoengineering approaches to the manipulation of the cell surface Unlocks the potential of cell surface manipulation for a range of new applications in the fields of in vitro research, cell therapy, tissue engineering, biosensing, and diagnostics

List of Contributors


Ayman F. Abuelela,     Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Kingdom of Saudi Arabia

Rangoli Aeran,     Department of Pharmaceutical Sciences, Chao and Family Comprehensive Cancer Center, Sue and Bill Gross Stem Cell Research Center, Edwards Lifesciences Center for Advanced Cardiovascular Technology, Department of Biomedical Engineering, University of California, Irvine, CA, USA

Kawther K. Ahmed,     College of Pharmacy, University of Iowa, Iowa City, IA, USA

Laura Alberch,     Department of Biomedical Engineering and the Translational Tissue Engineering Center, The Johns Hopkins University, Baltimore, MD, USA

Priya Anandakumaran,     Division of Biomedical Engineering, Department of Medicine, Center for Regenerative Therapeutics, Brigham and Women’s Hospital, Boston, MA; Harvard Medical School, Harvard University, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA

Maniraj Bhagawati,     Department of Bioengineering, University of California, Berkeley, CA, USA

Elliot L. Chaikof,     Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA; Harvard Medical School, Boston, MA; Wyss Institute for Biological Inspired Engineering of Harvard University, Cambridge, MA, USA

Jian Du,     Department of Biomedical Engineering and the Translational Tissue Engineering Center, The Johns Hopkins University, Baltimore, MA, USA

Debjit Dutta,     Institute for Stem Cell Biology and Regenerative Medicine, National Centre for Biological Sciences-Campus, UAS-GKVK, Bangalore, India

Wade M. Fox,     Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, USA

Samir Gautam,     Department of Cell Biology, Yale School of Medicine, New Haven, CT, USA

Sean M. Geary,     College of Pharmacy, University of Iowa, Iowa City, IA, USA

Edward Han,     Division of Biomedical Engineering, Department of Medicine, Center for Regenerative Therapeutics, Brigham and Women’s Hospital, Boston, MA; Harvard Medical School, Harvard University, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA

Dong-Ku Kang,     Department of Pharmaceutical Sciences, Chao and Family Comprehensive Cancer Center, Sue and Bill Gross Stem Cell Research Center, Edwards Lifesciences Center for Advanced Cardiovascular Technology, Department of Biomedical Engineering, University of California, Irvine, CA, USA

Jeffrey M. Karp,     Division of Biomedical Engineering, Department of Medicine, Center for Regenerative Therapeutics, Brigham and Women’s Hospital, Boston, MA; Harvard Medical School, Harvard University, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA

Alexey Y. Koyfman,     Department of Biochemistry and Molecular Biology, and Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, USA

Sanjay Kumar,     Department of Bioengineering, University of California, Berkeley, CA, USA

X. Chris Le,     Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada

Oren Levy,     Division of Biomedical Engineering, Department of Medicine, Center for Regenerative Therapeutics, Brigham and Women’s Hospital, Boston, MA; Harvard Medical School, Harvard University, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA

Feng Li,     Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada; Department of Pharmaceutical Sciences, Chao and Family Comprehensive Cancer Center, Sue and Bill Gross Stem Cell Research Center, Edwards Lifesciences Center for Advanced Cardiovascular Technology, Department of Biomedical Engineering, University of California, Irvine, CA, USA

Linan Liu,     Department of Pharmaceutical Sciences, Chao and Family Comprehensive Cancer Center, Sue and Bill Gross Stem Cell Research Center, Edwards Lifesciences Center for Advanced Cardiovascular Technology, Department of Biomedical Engineering, University of California, Irvine, CA, USA

Srujan K. Marepally,     Institute for Stem Cell Biology and Regenerative Medicine, National Centre for Biological Sciences-Campus, UAS-GKVK, Bangalore, India

Jasmeen S. Merzaban,     Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Kingdom of Saudi Arabia

Riddhima Minocha,     Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore

Kelvin S. Ng,     Division of Biomedical Engineering, Department of Medicine, Center for Regenerative Therapeutics, Brigham and Women’s Hospital, Boston, MA; Harvard Medical School, Harvard University, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA

Jessica Ngai,     Division of Biomedical Engineering, Department of Medicine, Center for Regenerative Therapeutics, Brigham and Women’s Hospital, Boston, MA; Harvard Medical School, Harvard University, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA

Jaina M. Patel,     Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA

Egest J. Pone,     Department of Pharmaceutical Sciences, Chao and Family Comprehensive Cancer Center, Sue and Bill Gross Stem Cell Research Center, Edwards Lifesciences Center for Advanced Cardiovascular Technology, Department of Biomedical Engineering, University of California, Irvine, CA, USA

Norbert O. Reich,     Biomolecular Science and Engineering Program, and Department of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, CA, USA

Kosuke Sakashita,     Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Kingdom of Saudi Arabia

Aliasger K. Salem,     College of Pharmacy, University of Iowa, Iowa City, IA, USA

Debanjan Sarkar,     Department of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY USA

Periasamy Selvaraj,     Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA

David A. Spiegel,     Department of Chemistry, Yale University, New Haven, CT, USA; Department of Pharmacology, Yale University, New Haven, CT, USA

Zhixiang Tong,     Division of Biomedical Engineering, Department of Medicine, Center for Regenerative Therapeutics, Brigham and Women’s Hospital, Boston, MA; Harvard Medical School, Harvard University, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA

Mark L. Tykocinski,     Department of Pathology, Anatomy and Cell Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA

Vincent F. Vartabedian,     Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA

Praveen Kumar Vemula,     Institute for Stem Cell Biology and Regenerative Medicine, National Centre for...

Erscheint lt. Verlag 30.5.2014
Sprache englisch
Themenwelt Naturwissenschaften Biologie Zellbiologie
Technik Bauwesen
Technik Maschinenbau
Technik Umwelttechnik / Biotechnologie
ISBN-10 1-4557-3155-2 / 1455731552
ISBN-13 978-1-4557-3155-8 / 9781455731558
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