Nanomaterial (eBook)

Impacts on Cell Biology and Medicine
eBook Download: PDF
2014 | 2014
XI, 278 Seiten
Springer Netherlands (Verlag)
978-94-017-8739-0 (ISBN)

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The rapidly developing field of nanomaterials has expanded in many commercial areas. More recent studies have begun to provide a foundation for understanding how nanomaterials influence cells and how they also can serve as methodological tools for studies in medicine and cell biology, including research into stem cells. Recent investigations have shown affects of nanomaterials on specific subcellular structures, such as the actin-based brush border network in cells with an increasing emphasis on the barrier function of epithelial tissues. While other studies have shown involvement of nanoparticles in specific cytoplasmic signal transduction events such as the rise in intracellular free calcium, a signaling event known to regulate many changes in cell architecture and function. In parallel, nanomaterials are increasingly used in medicine for drug delivery, treatment of cancer and an increasing number of new applications. This book investigates these areas and also includes new methods for assessment in cell biology and medicine.
The rapidly developing field of nanomaterials has expanded in many commercial areas. More recent studies have begun to provide a foundation for understanding how nanomaterials influence cells and how they also can serve as methodological tools for studies in medicine and cell biology, including research into stem cells. Recent investigations have shown affects of nanomaterials on specific subcellular structures, such as the actin-based brush border network in cells with an increasing emphasis on the barrier function of epithelial tissues. While other studies have shown involvement of nanoparticles in specific cytoplasmic signal transduction events such as the rise in intracellular free calcium, a signaling event known to regulate many changes in cell architecture and function. In parallel, nanomaterials are increasingly used in medicine for drug delivery, treatment of cancer and an increasing number of new applications. This book investigates these areas and also includes new methods for assessment in cell biology and medicine.

1 Presence in, and release of, nanomaterials from consumer products Yu Yang and Paul Westerhoff2 Nanoparticle aggregation: Principles and modelingWen Zhang 3  Influences of nanomaterials on the barrier function of epithelial cellsShariq Ali and Erik Rytting4 Engineered nanoparticles induced brush border disruption in a human model of the intestinal epitheliumJames J. Faust, Benjamin M. Masserano, Adam H. Mielke, Anup Abraham, and David G. Capco 5 Nanoparticles: Cellular uptake and cytotoxicityIsaac  M. Adjei,  Blanka Sharma and Vinod Labhasetwar6 Atomic force microscopy study of the interaction of DNA and nanoparticlesKungang LI, Songyan Du, Steven Van Ginkel, and Yongsheng Chen7 Intracellular signal modulation by nanomaterialsSalik Hussain, Stavros Garantziotis, Fernando Rodrigues-Lima, Jean-Marie Dupret, Armelle Baeza-Squiban, Sonja Boland8 Nanomaterials: Impacts on cells and cell organelles Željka Krpetić, Sergio Anguissola, David Garry, Philip Kelly and Kenneth A. Dawson9 Design, synthesis, and functionalization of nanoparticles for therapeutic drug deliveryTaraka Sai Pavan Grandhi and Kaushal Rege10 Preparation of nanoscale pulmonary drug delivery formulations by spray dryingAdam Bohr, Christian A. Ruge, and Moritz Beck-Broichsitter11 Nanomedicine: The Promise and Challenges in Cancer ChemotherapyAuthor:  Youssef W. Naguib and Zhengrong Cui12 Transgenerational effects of NMsAnna Poma, Sabrina Colafarina,  Gabriella Fontecchio, , and Giuseppe Chichiricco13 Stem cells and nanomaterialsMaria-Claude HofmannIndex

Erscheint lt. Verlag 28.3.2014
Reihe/Serie Advances in Experimental Medicine and Biology
Zusatzinfo XI, 278 p. 70 illus., 42 illus. in color.
Verlagsort Dordrecht
Sprache englisch
Themenwelt Medizin / Pharmazie Physiotherapie / Ergotherapie Orthopädie
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Naturwissenschaften Biologie Zellbiologie
Technik Maschinenbau
Technik Medizintechnik
Schlagworte Cell Biology • Cytotoxicity • Drug Delivery • epithelial cells • nanomaterials • nanotoxicology • Stem Cells
ISBN-10 94-017-8739-5 / 9401787395
ISBN-13 978-94-017-8739-0 / 9789401787390
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