Nephrotoxic Mechanisms of Drugs and Environmental Toxins
Springer-Verlag New York Inc.
978-1-4684-4216-8 (ISBN)
Section I. Pathophysiology of Acute Renal Failure.- 1. Overview of Pathophysiology of Acute Renal Failure.- 2. Pathology of Acute Renal Failure.- 3. Effect of Heavy Metals on Sodium Transport in Vitro.- 4. Renal Hemodynamics in Nephrotoxic Acute Renal Failure.- 5. The Glomerulus in Acute Renal Failure.- 6. Heavy Metal Models of Experimental Acute Renal Failure.- 7. Studies on Segmental Transport in Models of Acute Renal Failure.- 8. Enhancement of Renal Regeneration by Amino Acid Administration.- 9. Amphotericin B Toxicity for Epithelial Cells.- Section II. Renal Failure Due to Antimicrobial Agents.- 10. Antibiotic Nephrotoxicity: An Overview.- 11. Functional Considerations in Aminoglycoside Nephrotoxicity.- 12. Aminoglycoside Nephrotoxicity: Lysosomal and Mitochondrial Alterations in Rat Kidneys after Aminoglycoside Treatment.- 13. Aminoglycoside Interactions with Other Drugs: Clinical and Toxicologic Implications.- 14. Nephrotoxicity of Cephalosporin Antibiotics: Mechanisms and Modifying Factors.- 15. Tetracycline Nephrotoxicity.- Section III. Tubulointerstitial Nephropathy Due to Drugs and Environmental Toxicants.- 16. Tubulointerstitial Nephropathy: An Overview.- 17. Current Concepts of Tubulointerstitial Nephritis.- 18. Analgesic Nephropathy: Clinical and Epidemiologic Factors.- 19. Analgesic Nephropathy: Renal Drug Distribution and Metabolism.- 20. Endemic Balkan Nephropathy.- 21. Nephrotoxicity of Natural Products: Mycotoxin-Induced Nephropathy.- 22. Lead Nephrotoxicity.- 23. The Rat as an Animal Model of Lead Nephropathy.- Section IV. Pathophysiologic Mechanisms of Toxicity Induced by Environmental Toxins Jerry.- 24. Environmental Toxicities and Hazards: Introduction.- 25. Metabolism of Cadmium.- 26. Cadmium Nephropathy.- 27. Ultrastructural and Biochemical Localization of Organelle Damage from Nephrotoxic Agents.- 28. Mechanisms of Acute Nephrotoxicity: Halogenated Aliphatic Hydrocarbons.- 29. Potentiation of the Action of Nephrotoxic Agents by Environmental Contaminants.- 30. Alteration of Chloroform-Induced Nephrotoxicity by Exogenous Ketones.- Section V. Immunologic Mechanisms and Toxic Nephropathies.- 31. Drug-Induced Renal Lesions: Immunopathologic Mechanisms.- 32. Antihistone Antibodies Induced by Procainamide and Hydralazine.- 33. Drug- and Toxin-Induced Nephritides: Anti-Kidney Antibody and Immune Complex Mediation.- 34. Immunological Mechanisms in Drug-Induced Acute Interstitial Nephritis.- 35. Drug-Induced Nephritides: Immediate Hypersensitivity Mechanism.- 36. Gold-Induced Autoimmune Reactions.- 37. Mercuric Chloride-Induced Immunologically Mediated Diseases in Experimental Animals.- 38. Genetic Control of Mercury-Induced Immune Response in the Rat.- 39. The Application of a Radioimmunoassay for Sensitive Detection of Metallothionein (Thionein) in Physiologic Fluid of Humans and Rats.
Zusatzinfo | 29 Illustrations, black and white; XIX, 466 p. 29 illus. |
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Verlagsort | New York, NY |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Naturwissenschaften ► Chemie ► Organische Chemie |
ISBN-10 | 1-4684-4216-3 / 1468442163 |
ISBN-13 | 978-1-4684-4216-8 / 9781468442168 |
Zustand | Neuware |
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