Advances in Protein Chemistry and Structural Biology

Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.

Bioinformatics Tools to Identify and Quantify Proteins using Mass Spectrometry Data
Soyoung Ryu

Unraveling Oxidation-Induced Modifications in Proteins by Proteomics
Carolina Panis

Role of Proteomics in Biomarker Discovery: Prognosis and Diagnosis of Neuropsychiatric Disorders
Suman Patel

On the use of Knowledge-Based Potentials for the Evaluation of Models of Protein–Protein, Protein–DNA and Protein–RNA Interactions
Oriol Fornes, Javier Garcia-Garcia, Jaume Bonet and Baldo Oliva

Algorithms, Applications and Challenges of Protein Structure Alignment
Jianzhu Ma and Sheng Wang

Application of Evolutionary based in silico Methods to Predict the Impact of Single Amino Acid Substitutions in Vitelliform Macular Dystrophy
C. George Priya Doss, Chiranjib Chakraborty, N. Monford Paul Abishek, D. Thirumal Kumar and Vaishnavi Narayanan

Current State of the Art Molecular Dynamics Methods and Applications
Dimitrios Vlachakis, Elena Bencurova, Nikitas Papangelopoulos and Sophia Kossida

Intrinsically Disordered Proteins – Relation to General Model Expressing the Active Role of the Water Environment
Barbara Kalinowska, Mateusz Banach, Leszek Konieczny, Damian Marchewka and Irena Roterman

Conformational Elasticity can Facilitate TALE-DNA Recognition
Hongxing Lei, Jiya Sun, Enoch P. Baldwin, David J. Segal and Yong Duan

Computational Approaches and Resources in Single Amino Acid Substitutions Analysis towards Clinical Research C. George Priya Doss, Chiranjib Chakraborty, Vaishnavi Narayan and D. Thirumal Kumar