Binding, Transport and Storage of Metal Ions in Biological Cells

Wolfgang Maret FRSC obtained his MSc (chemistry) and PhD (natural sciences) from Saarland University, Saarbrücken, Germany.  After postdoctoral research at the University of Chicago (Department of Biophysics &Theoretical Biology), his first faculty appointment was at Harvard Medical School.  In 2002, he joined the University of Texas Medical Branch in Galveston, Texas as an Associate Professor.  He is now a Professor of Metallomics at King’s College London, London, UK.  His research interests began with the catalytic mechanisms of metalloenzymes as investigated with spectroscopic and kinetic methods and continued with the role of metal ions in health and disease, the molecular mechanisms of how proteins control metal ions, and the cellular mechanism of how metal ions control protein structure and function. Anthony G Wedd is Tasmanian by birth and holds both PhD and DSc from the University of Tasmania. He spent a postdoctoral period with Professor Joseph Chatt (University of Sussex) before becoming a staff member at La Trobe University in Melbourne, Australia. He transferred to the University of Melbourne in 1991 as a Professor of Chemistry.  His long term interests have been in polyoxometalate cluster chemistry and in biological inorganic chemistry, and particularly the relevant chemistries of molybdenum, tungsten and copper.

Overview;

Sodium: Its Role in Bacterial Metabolism;

Potassium;

Magnesium;

Calcium;

Vanadium;

Chromium;

Molybdenum and Tungsten;

Manganese;

Iron in Eukarya;

Iron Uptake and Homeostasis in Prokaryotic Microorganisms;

Iron-Sulfur Clusters;

Ferritin and its Role in Iron Homeostasis;

Cobalt and Nickel;

Platinum;

Binding, Transport and Storage of Copper in Prokaryotes;

Binding, Transport, and Storage of Copper in Mitochondria;

Binding, Transport and Storage of Copper in Eukaryotes;

Silver;

Gold;

Metallothioneins;

Zinc;

Cadmium;

Mercury;

Antimony and Bismuth;

Actinides in Biological Systems;

Aluminium;

Binding, Transport and Storage of Lead;