Physical Properties of Biological Membranes and Their Functional Implications

1 Structural Studies on Phospholipid Bilayers by X-Ray Fiber Diffraction Methods.- 1. Introduction.- 2. X-Ray Fiber Diagrams.- 3. Specimen Preparation.- 4. Photographic Equipment and Technique.- 5. Geometrical Measurement of the Reflections and Information Provided.- 6. Intensities of the Reflections.- 7. Electron Density.- 8. Experimental Observations.- 9. Conclusions.- References.- 2 2H and 13C NMR Spectroscopy of Lipid Model Membranes Alfred Blume.- 1. Introduction.- 2. Principles and Methods.- 3. Applications of 13C and 2H NMR to Lipid Model Membranes.- 4. Summary.- References.- 3 Applications of Calorimetry to Lipid Model Membranes.- 1. Introduction.- 2. Differential Scanning Calorimetry.- 3. Reaction Calorimety.- 4. Conclusions.- References.- 4 Molecular Mobility in Membranes.- 1. Introduction.- 2. Lateral Diffusion.- 3. Rotational Diffusion.- References.- 5 The Acetylcholine Receptor and its Membrane Environment.- 1. Introduction.- 2. Acetylcholine Receptor Primary Structure, cDNA Recombinant Techniques, and Acetylcholine Receptor Models.- 3. Acetylcholine Receptor-Mediated Channel Gating: A Single Molecule at Work.- 4. The Acetylcholine Receptor in the Lipid Bilayer.- 5. Dynamics of Acetylcholine Receptor and Lipids in the Membrane.- References.- 6 Fluorescence Spectroscopy in the Study of Sarcoplasmic Reticulum Calcium-ATPase.- 1. Introduction.- 2. Structure and Conformation.- 3. Macromolecular Association.- 4. Protein—Protein and Protein—Lipid Interactions.- References.- 7 Lipid—Protein Interactions in the Function of the Na+ and H+ Pumps: Role of Sulfatide.- 1. Introduction.- 2. The Sodium Pump.- 3. Lipid Requirements of the Sodium Pump: Role of Sulfatides.- 4. Role of Sulfatides in the Proton Pump.- 5. Conclusions.- References.