New Developments in Biosciences: Their Implications for Laboratory Animal Science

Opening Address: The Future of Laboratory Animal Use.- The Acquired Immunedeficiency Syndrome in Man.- Feline Acquired Immunodeficiency Syndromes.- Immune Deficiency Syndrome in Rodents: The Nude Rat.- Animal Welfare — Common Interest.- Laboratory Animal ....... Science — Service — Use.- Laboratory Animal Science in Czechoslovakia.- On the Ethology of Pain, its Experience and Expression.- Pain in Neonates.- Endorphins and Pain.- Effects of Exogenous Pain Relieving Substances on Experimental Results.- Veterinary Care at the Primate Center TNO.- Developing Housing Facilities for Rhesus Monkeys: Prevention of Abnormal Behaviour.- Microbiological Quality Assurance and Quality Assessment of Laboratory Animals.- Centralisation — Decentralisation: Failure — Success.- The Effect of Homogenization and Pasteurization on the Allergenicity of Bovine Milk Analysed by a Murine Anaphylactic Shock Model.- Murine Passive Cutaneous Anaphylaxis Test (PCA) for the “All or None” Determination of Allergenicity of Bovine Whey Proteins and Peptides.- Phenotypic and Patho-Morphological Characteristics in a Half-Sib-Family of Transgenic Mice Carrying Foreign MT-HGH Genes.- The Housing and Handling of Marmosets and Tamarins Infected With Aids and Other Retroviruses.- Long-Term Observation of Litter Intervals in Permanently Monogamous Mated Han:NMRI Mice.- Genital Inflammation in Male Mice. A Microbiological Study.- Microbial Assessment of a Single Fumigation by Formaldehyde of a Multi-Level Animal Facility.- Mechanisms of Natural Selection Maintaining in Groups of Highly Standardized Mice and Rats, Influence on Infection Resistance.- Provocation of Latent Infections.- to Recombinant DNA Technology.- DNA Hybridization as a Tool in Diagnosing Infectious Diseases. Comparison With OtherMethods..- Embryo Transfer and Manipulation.- Strain Preservation of Rodent Embryos. Possibilities and Limitations.- The Generation of Transgenic Animals and Their Use in Fundamental Research.- On the Inheritance of Blood Characters in Mice.- Investigating Genetic Variability Between the MHS Hypertensive Strain of Rats and its Normotensive Control, MNS.- Gene Mapping and Linkage Homology.- A New Method to Produce Artificial Monozygotic Twins in Mice.- Genetic Analysis of Multigenic Traits Using the Recombinant Congenic Strains.- Acute Dermal Toxicity: Morphological Response of the Hairless Mice Skin Organ Culture.- The Dutch Rabbit in Toxicity Testing. Chemical-Induced Creatine Kinase Release; A Species- and Strain-Specific Response?.- Intertrial-Interval in the “Water Escape Test” in Mice.- Behaviour, Housing and Welfare of Non-Human Primates.- Housing and Welfare of Laboratory Rodents.- Housing Conditions and Experimental Results.- Basis of the European Guidelines: Facts or Intuition?.- Gnotobiotic Animals in Nutrition Research.- Animal Models for Cholesterol Metabolism Studies.- Animal Models in Hemostasis and Thrombosis.- Mice with Ulcerating Lesions on the Nose, Limbs and/or Tail.- Spontaneous Hyperplasia of the Endometrium in the Rabbit.- Monkey Graffity: Environmental Deficiency, Boredom or Artistic Drive?.- Marking of African Clawed Toads (Xenopus laevis). Improvement of a Skin Autograft Technique.- Changes in Energy Intake, Body Weight Gains, Average Feed Efficiency and Some Plasma Hormone Levels in Dogs from Different Environments.- Serum Concentrations of Vitamins A, D and E of Growing Beagles Fed Commercial Dog and Fox Diets.- Integration of HGH Gene in Transgenic Mice and Transmission to Next Generation.- Attempts to Produce Transgenic Rabbits CarryingMTI-HGH Recombinant Gene.- Electrofusion of Early Mammalian Embryo Cells.- Passive Infrared Movement Detector, A New Equipment to Monitor Motor Activity of Small Rodents in Normal Cages.- Establishment of a SPF Population of Cricetulus griseus.- Chronic Phlorizin Intoxication in Adipose Mutant Mice C57BL/KS db/db and in Normal Controls.- Plasma ?-Amylase and Lipase Activities in Dogs with Variations in Food Composition and Availability.- Locomotor Activity of a Behavior Mutant in NMRI Mice.- The Application of Embryo Transfer and Cryopreservation to Commercial Laboratory Animal Breeding.- Serological Following of a Laboratory Rat Breeding Contaminated with Respiratory Viruses During 1981–1986.- Eradication of Encephalitozoonosis in Rabbit Breeding Colonies by Carbon Immunoassay.- Spontaneous Murine Hemosiderosis, A Model for Human Hemochromatosis?.- In Vitro Adhesion of K88 Positive E. Coli to Intestinal Villi of Just-Weaned Piglets.- The Effects of Gentling on Open-Field Behaviour of Rats.- Blastomere-Karyotyping: A Direct Method for Producing Mouse Trisomy 16 ? Diploid Aggregation Chimeras as an Animal Model of Human Down’s Syndrome.- A Proposed Species Difference in the Renal Excretion of Perfluoro Octanoic Acid in the Beagle Dog and Rat.- Measurement of Orthostatic Responses in Conscious Dogs.- Oral 65Zn Loading Test in Rats FED IRI-OB Diet with Various Zn Concentrations.- Mortality and Tumour Incidence of BDII/Han Rats.- Assessment of Discomfort Induced by Orbital Functure in Rats.- Effect of Morphinomimetics in Different Pain Tests.- Prevention of Early Deaths in Mice Contaminated with Gram Negative Enteric Bacteria and Fungus Following Irradiation.- Detection of Mycoplasma neurolyticum in a Colony of Inbred Mice: Clinically Silent Infection.- Effects ofHandling and Transportation Stress on Rodents.