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Pathogenicity Islands and the Evolution of Pathogenic Microbes

Volume I

J. Hacker, J.B. Kaper (Herausgeber)

Buch | Softcover

XXXIV, 444 Seiten

2002 | 1. Softcover reprint of the original 1st ed. 2002
Springer Berlin (Verlag)
978-3-540-42682-0 (ISBN)

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It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.

List of Contents.- Evolution of Prokaryotic Genomes.- Extraintestinal Escherichia coli as a Model System for the Study of Pathogenicity Islands.- Pathogenicity Islands of Intestinal E. coli.- Pathogenicity Islands of Shigella.- Pathogenicity Islands and Host Adaptation of Salmonella Serovars.- Plasmids and Pathogenicity Islands of Yersinia.- Genomic Organization of LPS-Specific Loci.- Genomic Structure of Capsular Determinants.- Genome Plasticity in Pathogenic and Nonpathogenic Enterobacteria.- Phylogenetic Relationships and Virulence Evolution in the Genus Bordetella.- Pathogenicity Islands and PAI-Like Structures in Pseudomonas Species.

From the reviews:

"This compendium brought together by J. Hacker and J. B. Kaper as editors, features an international assembly of authors ... giving a lucid introduction into the evolution of prokaryotic genomes. The ... work provides a comprehensive overview of the current state of knowledge on PAIs and other mobile virulence determinants in bacterial as well as fungal pathogens of humans and plants." (Susanne Rohrer, BioWorld, Issue 61, 2002)

Erscheint lt. Verlag	12.3.2002
Reihe/Serie	Current Topics in Microbiology and Immunology
Zusatzinfo	XXXIV, 444 p.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	531 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin
	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
Schlagworte	Bacillus cereus • Bacteria • Dichelobacter nodosus • DNA • Escherichia coli • Fungi • Gene • genes • gene transfer • genome structure • Helicobacter pylori • Legionella • Listeria • microbe • microbes • Neisseria • pathogenesis • pathogenic fungi • Pseudomonas • resistance • yersinia
ISBN-10	3-540-42682-5 / 3540426825
ISBN-13	978-3-540-42682-0 / 9783540426820
Zustand	Neuware