Genes, Development and Cancer
Springer-Verlag New York Inc.
978-1-4613-4746-0 (ISBN)
- Commentaries by Howard Lipshitz highlight key methods and results by explaining the science so it is accessible to upper-level undergraduates, graduate students, and professional researchers
- For the first time, Nobel Prize winner, Edward B. Lewis' research papers are published within one volume
- Papers are organized into sections that reflect the focus of the research
- Commentaries by Howard Lipshitz highlight key methods and results by explaining the science so it is accessible to upper-level undergraduates, graduate students, and professional researchers
Background -Invention of the cis-trans test for position effects -Position pseudoalleles -The bithorax pseudoalleles and the concept of developmental control -Gene evolution by tandem duplication -From cisvection to transvection- Extending the bithorax pseudoallelic series -Genetic versus functional models -From genes to gene complexes -Developmental genetics -Gain-of-function and loss-of-function alleles, and the operon model -Genetic mosaics: spatial and temporal aspects of bithorax function -The 1978 paper: a paradigm for the genetic control of development -Trans-acting regulators: positive and negative control of the homeotic complexes -Cis-regulation within the BX-C: the rules of engagement -Positional cloning of the BX-C -Completing the bithorax mutant series -The molecular basis of developmental control -Bithorax and the evolution of sexually dimorphic traits -DNA sequence motifs in the cis-regulatory regions of the BX-C -Evolution of the HOX complexes -Genetic and somatic effects of ionizing radiation -The political and social context -Leukemia and ionizing radiation -Political fallout -Thyroid radiation doses from weapons fallout -Best estimates of risk: leukemia in populations exposed to low doses of radiation -Estimates of lung cancer risk: the Batelle beagles
| Zusatzinfo | XVI, 557 p. |
|---|---|
| Verlagsort | New York, NY |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 872 g |
| Themenwelt | Literatur ► Biografien / Erfahrungsberichte |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
| Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| ISBN-10 | 1-4613-4746-7 / 1461347467 |
| ISBN-13 | 978-1-4613-4746-0 / 9781461347460 |
| Zustand | Neuware |
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