Macrophages and Related Cells -

Macrophages and Related Cells

Michael A. Horton (Herausgeber)

Buch | Softcover
434 Seiten
2013 | Softcover reprint of the original 1st ed. 1993
Springer-Verlag New York Inc.
978-1-4757-9536-3 (ISBN)
213,99 inkl. MwSt
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The Mononuclear Phagocyte System . 1 A Structural Approach to Classification . 6 . 3 Soluble Receptors . 1 Growth, Differentiation, and Modulation . 4 Secretory Responses and Biosynthesis of Effector Molecules . Concluding Remarks . 18 .
To produce a comprehensive overview of macrophages and related cell types in a short review volume is an impossible task. When I selected the topics to be included, some equally important areas were omitted by necessity, and for this I apologize. My choices have been somewhat eclectic, touching subjects of personal interest (such as osteoclast biology and macrophage electrophysiology) or of current fashion (apopto­ sis, antigen processing, cell adhesion molecules). The book has also had to encompass areas of a more general flavor to provide balance for the general reader (such as reviews of macrophage development, heterogeneity, and function, and of the surface molecules expressed by macrophages). I thank all the authors for their prompt sub­ missions; all have been of high quality, and my editorial tasks, thankfully, have been minimal. Michael A. Horton London, United Kingdom ix Contents Chapter J An Overview of Receptors of MPS Cells lain Fraser and Siam on Gordon 1. Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2. The Mononuclear Phagocyte System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 3. Diversity of Macrophage Plasma Membrane Receptors. . . . . . . . . . . . . . . . 6 3. 1 A Structural Approach to Classification . . . . . . . . . . . . . . . . . . . . . . . . . . 6 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 3. 2 Multisubunit Receptors 3. 3 Soluble Receptors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 3. 4 Lectins and Lectin-Like Receptors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 4. Functions and Selected Examples. . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . 14 4. 1 Growth, Differentiation, and Modulation . . . . . . . . . . . . . . . . . . . . . . . . 14 4. 2 Cell-Cell and Cell-Matrix Interactions. . . . . . . . . . . . . . . . . . . . . . . . . . . 16 4. 3 Endocytosis and Scavenger Receptors. . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 4. 4 Secretory Responses and Biosynthesis of Effector Molecules . . . . . . 17 5. Concluding Remarks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 6. References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 . . . . . . . . . . . . . . . . . . . .

1 An Overview of Receptors of MPS Cells.- 2 Heterogeneity of Mononuclear Phagocytes: An Interpretive Review.- 3 Origin of Macrophages.- 4 Complement and the Mononuclear Phagocyte System.- 5 Macrophages and Prostaglandins.- 6 Antigen Processing.- 7 Antigens of Osteoclasts: Phenotypic Definition of a Specialized Hemopoietic Cell Lineage.- 8 Electrophysiology of Osteoclasts and Macrophages.- 9 Complement Receptors.- 10 Fc? Receptors of Myeloid Cells.- 11 Matrix Receptors of Myeloid Cells.- 12 Leukocyte Integrins.- 13 Molecular Basis for Leukocyte Adhesion Molecule Deficiency.- 14 Carbohydrate-Recognition Proteins of Macrophages and Related Cells.- 15 Leukocyte Adhesion to Endothelium.- 16 Cell Recognition of Apoptotic Cells.

Reihe/Serie Blood Cell Biochemistry ; 5
Zusatzinfo XIX, 434 p.
Verlagsort New York, NY
Sprache englisch
Maße 178 x 254 mm
Themenwelt Medizinische Fachgebiete Innere Medizin Hämatologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Studium 2. Studienabschnitt (Klinik) Humangenetik
Studium Querschnittsbereiche Infektiologie / Immunologie
Naturwissenschaften Biologie Biochemie
ISBN-10 1-4757-9536-X / 147579536X
ISBN-13 978-1-4757-9536-3 / 9781475795363
Zustand Neuware
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