Peroxisomes and their Key Role in Cellular Signaling and Metabolism (eBook)
XII, 350 Seiten
Springer Netherland (Verlag)
978-94-007-6889-5 (ISBN)
Peroxisomes are a class of ubiquitous and dynamic single membrane-bounded cell organelles, devoid of DNA, with an essentially oxidative type of metabolism. In recent years it has become increasingly clear that peroxisomes are involved in a range of important cellular functions in almost all eukaryotic cells. In higher eukaryotes, including humans, peroxisomes catalyze ether phospholipids biosynthesis, fatty acid alpha-oxidation, glyoxylate detoxification, etc, and in humans peroxisomes are associated with several important genetic diseases. In plants, peroxisomes carry out the fatty acid beta-oxidation, photorespiration, metabolism of ROS, RNS and RSS, photomorphogenesis, biosynthesis of phytohormones, senescence, and defence against pathogens and herbivores. In recent years it has been postulated a possible contribution of peroxisomes to cellular signaling. In this volume an updated view of the capacity and function of peroxisomes from human, animal, fungal and plant origin as cell generators of different signal molecules involved in distinct processes of high physiological importance is presented.
DedicationPreface1. Peroxisome interactions and cross-talk with other subcellular compartments in animal cells; Michael Schrader, Sandra Grille, H. Dariush Fahimi and Markus Islinger2. Peroxisomes in human health and disease: metabolic pathways, metabolite transport, interplay with other organelles and signal transduction; Ronald J.A. Wanders 3. Aging, age-related diseases and peroxisomes; Marc Fransen, Marcus Nordgren, Bo Wang, Oksana Apanasets and Paul P. Van Veldhoven 4. Peroxisomes and the antiviral responses of mammalian cells; Charlotte Odendall and Jonathan C. Kagan 5. Peroxisome proliferator-activated receptor-α signaling in hepatocarcinogenesis; Parimal Misra, Navin Viswakarma and Janardan K. Reddy 6. Involvement of human peroxisomes in biosynthesis and signaling of steroid and peptide hormones; Isabelle Weinhofer, Markus Kunze, Sonja Forss-Petter and Johannes Berger 7. Peroxisome Ca2+ homeostasis in animal and plant cells; Alex Costa, Ilaria Drago, Michela Zottini, Paola Pizzo and Tullio Pozzan8. The versatility of peroxisome function in filamentous fungi; Ida J. van der Klei and Marten Veenhuis9. Essential roles of peroxisomally produced and metabolized biomolecules in regulating yeast longevity; Adam Beach and Vladimir I. Titorenko 10. Metabolite transporters of the plant peroxisomal membrane - known and unknown; Nicole Linka and Frederica L. Theodoulou11. Peroxisomes and photomorphogenesis; Navneet Kaur, Jiying Li, and Jianping Hu12. Biosynthesis of vitamin K1 (phylloquinone) by plant peroxisomes and its integration into signaling molecule synthesis pathways; Sigrun Reumann 13. Role of peroxisomes as a source of reactive oxygen species (ROS) signaling molecules; Luisa M. Sandalio, María Rodríguez-Serrano, María C. Romero-Puertas and Luis A. del Río14. Peroxisomes as a source of auxin signaling molecules; Gretchen M. Spiess and Bethany K. Zolman15. Peroxisomes as cell generators of reactive nitrogen species (RNS) signal molecules; Francisco J. Corpas, Juan B. Barroso, José M Palma and Luis A. del Río 16. Role of plant peroxisomes in the production of jasmonic acid-based signals; José León 17. Role of plant peroxisomes in protection against herbivores; Mohammed Shabab18. Function of Peroxisomes in Plant-Pathogen Interactions; Yasuyuki Kubo Index
Erscheint lt. Verlag | 3.7.2013 |
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Reihe/Serie | Subcellular Biochemistry | Subcellular Biochemistry |
Zusatzinfo | XII, 350 p. |
Verlagsort | Dordrecht |
Sprache | englisch |
Themenwelt | Medizin / Pharmazie ► Studium |
Naturwissenschaften ► Biologie ► Zellbiologie | |
Technik | |
Schlagworte | Cellular Signaling • Fungi and plants • Humans and Animals • Metabolism and signaling • Peroxisomes • Proteomics |
ISBN-10 | 94-007-6889-3 / 9400768893 |
ISBN-13 | 978-94-007-6889-5 / 9789400768895 |
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