Molecular and Functional Models in Neuropsychiatry -

Molecular and Functional Models in Neuropsychiatry

Jim J. Hagan (Herausgeber)

Buch | Softcover
XIV, 394 Seiten
2013 | 2011
Springer Berlin (Verlag)
978-3-642-26767-3 (ISBN)
246,09 inkl. MwSt
This book provides coverage of the state-of-the-art in Molecular and Functional Models in Neuropsychiatry. Animal models have a vital role to play in advancing this field. The book contains numerous illustrations and is written by leading experts in the field.
The development of more effective treatments for neuropsychiatric disorders requires scientific progress on a broad front. Animal models have a vital role to play in advancing the field. When deployed in conjunction with detailed study of these diseases in man they bring the power to make controlled experimental interventions which allow the functional consequences of genetic variations and polymorphisms to be understood in terms of their cellular, systems and behavioural effects. Further, they provide a means by which complex cognitive and behavioural phenomena may be dissected and understood. Finally, they provide a bridge to understanding the effects of drugs on the functioning of the central nervous system, thereby improving our understanding of the actions of those drugs in man.

From the contents: Preface.- Mouse mutagenesis and disease models for Neuropsychiatric disorders. - Drosophila as a model organism for the study of neuropsychiatric disorders.- Transgenic animal models of Huntington's Disease.- Molecular genetic models related to schizophrenia and psychotic illness: heuristics and challenges.- Animal Models of Depression: Molecular Perspectives.-Animal models of ADHD.- Mouse Models of Autism: Testing Hypotheses about Molecular Mechanisms.- Advances in animal models of drug addiction.- When the serotonin transporter gene meets adversity: The contribution of animal models to understanding epigenetic mechanisms in affective disorders and resilience.- Functional and Pharmacological MRI in understanding brain function at a systems level.- The pig as model animal for studying cognition and neurobehavioral disorders.

Erscheint lt. Verlag 29.5.2013
Reihe/Serie Current Topics in Behavioral Neurosciences
Zusatzinfo XIV, 394 p.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 623 g
Themenwelt Medizin / Pharmazie Studium
Naturwissenschaften Biologie Humanbiologie
Schlagworte Animal Models • Genetic • molecular • Neurology • Neuroscience • Psychiatry • Psychopharmacology
ISBN-10 3-642-26767-X / 364226767X
ISBN-13 978-3-642-26767-3 / 9783642267673
Zustand Neuware
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