Dynamics in Enzyme Catalysis

Buch | Hardcover
IX, 212 Seiten
2013 | 2013
Springer Berlin (Verlag)
978-3-642-38961-0 (ISBN)
213,99 inkl. MwSt
Christopher M. Cheatum and Amnon Kohen, Relationship of Femtosecond-Picosecond Dynamics to Enzyme-Catalyzed H-Transfer. Cindy Schulenburg and Donald Hilvert, Protein Conformational Disorder and Enzyme Catalysis. A. Joshua Wand, Veronica R. Moorman and Kyle W. Harpole,A Surprising Role for Conformational Entropy in Protein Function. Travis P. Schrank, James O. Wrabl and Vincent J. Hilser, Conformational Heterogeneity Within the LID Domain Mediates Substrate Binding to Escherichia coli Adenylate Kinase: Function Follows Fluctuations. Buyong Ma and Ruth Nussinov,Structured Crowding and Its Effects on Enzyme Catalysis. Michael D. Daily, Haibo Yu, George N. Phillips Jr and Qiang Cui, Allosteric Activation Transitions in Enzymes and Biomolecular Motors: Insights from Atomistic and Coarse-Grained Simulations. Karunesh Arora and Charles L. Brooks III, Multiple Intermediates, Diverse Conformations, and Cooperative Conformational Changes Underlie the Catalytic Hydride Transfer Reaction of Dihydrofolate Reductase. Steven D. Schwartz, Protein Dynamics and the Enzymatic Reaction Coordinate.

Relationship of Femtosecond-Picosecond Dynamics to Enzyme-Catalyzed H-Transfer.- Protein Conformational Disorder and Enzyme Catalysis.- A Surprising Role for Conformational Entropy in Protein Function.- Conformational Heterogeneity Within the LID Domain Mediates Substrate Binding to Escherichia coli Adenylate Kinase: Function Follows Fluctuations.- Structured Crowding and Its Effects on Enzyme Catalysis.- Allosteric Activation Transitions in Enzymes and Biomolecular Motors: Insights from Atomistic and Coarse-Grained Simulations.- Multiple Intermediates, Diverse Conformations, and Cooperative Conformational Changes Underlie the Catalytic Hydride Transfer Reaction of Dihydrofolate Reductase.- Protein Dynamics and the Enzymatic Reaction Coordinate.

Erscheint lt. Verlag 8.8.2013
Reihe/Serie Topics in Current Chemistry
Zusatzinfo IX, 212 p.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 502 g
Themenwelt Naturwissenschaften Biologie Biochemie
Naturwissenschaften Chemie Physikalische Chemie
Technik
Schlagworte Allostery • Cellular allosteric relay • Conformational disorder • Conformational entropy • Enzyme reaction coordinates • GTPases • Judith Klinman • Mechanochemical coupling • Protein dynamics • Sharon Hammes-Schiffer
ISBN-10 3-642-38961-9 / 3642389619
ISBN-13 978-3-642-38961-0 / 9783642389610
Zustand Neuware
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