Cell and Molecular Biology of the Ear

I: Mechanoreceptor Biology. 1. Kinociliary Mechanoreceptors in the Equilibrium Receptor Organs of Cephalopods; B.U. Budelmann. 2. Stereocilia Based Mechanoreceptors of Sea Anemones; G.M. Watson, P. Mire. 3. Plasma Membrane Ca2+-ATPase and Hair-Cell Function; R.A. Dumont, P.G. Gillespie. 4. Molecular Determinants of Hair Cell Phenotypic Heterogeneity - Differential Expression of K Channel Genes; D.S. Navaratnam, J.C. Oberholtzer. 5. Structural Basis of Outer Hair Cell Motility or Where's the Motor? W.E. Brownell, J.S. Oghalai. II: Developmental Biology of the Ear. 6. Induction of Ectodermal Placodes; C.V.H. Baker, et al. 7. A Model for Compartments and Boundaries in the Developing Inner Ear; D.M. Fekete, X. Gao. 8. Role of the POU-domain Transcription Factor Brn-3.1 in Hair Cell Development; A.F. Ryan. III: Genes and Deafness. 9. Genetic Linkage Studies of Hereditary Hearing Loss; W.J. Kimberling. 10. Mitochondrial Mutations and Hearing Loss; N. Fischel-Ghodsian. 11. Loss and Regeneration of Cochlear Hair Cell Innervation following Sound and Drug Damage; D.A. Cotanche, A.K. Hennig. 12. Mechanism and Prevention of Aminoglycoside-Induced Hearing Loss; S.-H. Sha, J. Schacht. 13. Neurotrophic Signaling by Membrane Electrical Activity in Spiral Ganglion Neurons; S. Green. 14. Protection of Cochlear Hair Cells from Gentamicin Ototoxicity and Mechanisms of Mammalian; W.-Q. Gao. 15. Protection and Regeneration of Vestibular Hair Cells - The Role of Neurotrophins after Gentamicin Ototoxicity; V. Honrubia, et al. IV: Gene-based Therapy for Sensorineural Hearing Loss. 16. Inner Ear Gene Therapy; Y. Raphael. 17. Adeno-Associated Virus Mediated Gene Transfer in the Peripheral Auditory System; A.K. Lalwani, et al. 18. Herpes simplex Viral Vector Gene-Based Therapy to Prevent Loss of Auditory Sensory Cells from Stress-Induced Apoptosis; H. Staecker, et al.