Advances in Hematopoietic Stem Cell Transplantation and Molecular Therapy

X, 150 Seiten
1998
Springer Berlin (Hersteller)
978-3-540-62626-8 (ISBN)

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These proceedings give an overview of the biology of haemotopoietic progenitor cells, peripheral stem cell transplantation in patients with haemotological malignancies, developments in molecular diagnosis and gene therapeutic concepts.
Blood stem cell transplantation has become an established therapeutic option in the treatment of malignant diseases. At the same time molecular therapeutic options (such as gene therapy) are promising alternatives to the classical treatment of cancer. These proceedings give an overview of the biology of haemotopoietic progenitor cells, peripheral stem cell transplantation in patients with haemotological malignancies, developments in molecular diagnosis and gene therapeutic concepts, and show that successful future developments require co-operative research connecting basic science with clinical application.

Mobilization and selection of CD34+cells; autologous stem cell transplantation for chronic myeloid leukaemia; autologous stem cell transplantation in aggressive non-Hodgkin's lymphoma; peripheral blood progenitor cell transplantation; molecular monitoring of residual disease in chronic myelogenous leukaemia patients after therapy; delineation of genomic regions; molecular cytogenetic analysis of low-grade C-cell neoplasias; applications of gene transfer; dendritic cells for somatic gene therapy; construction of immunogenic tumour cell surfaces; adeno-associated virus type 2 vector; protection of haemotopoietic stem cells; regulated gene expression after retroviral vector; specific bcr-abl-directed Antisende nucleic acids and ribozymes; the use of ribozymes in gene therapy approaches to AIDS.

Zusatzinfo 47 figs., 8 tabs.
Verlagsort Berlin
Sprache englisch
Gewicht 365 g
Einbandart gebunden
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Kernspintomographie (MRT)
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Nuklearmedizin
Medizin / Pharmazie Studium 1. Studienabschnitt (Vorklinik)
Naturwissenschaften Biologie Humanbiologie
ISBN-10 3-540-62626-3 / 3540626263
ISBN-13 978-3-540-62626-8 / 9783540626268
Zustand Neuware
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