Triple Helix Forming Oligonucleotides

Section I: Background and Structural Aspects.- 1 The Antigene Strategy: Progress and Perspectives in Selective Gene Silencing.- 2 Triple-Helix Structure: The Triple-Helix-Forming Oligonucleotide.- 3 Thermodynamic State Diagrams of Oligonucleotide Triple Helices.- 4 Imaging of Triplexes by Electron and Scanning Force Microscopy.- 5 Chemical Modifications of Triple Helix Forming Oligonucleotides.- 6 Triple Helix Formation with Modified Oligonucleotides.- 7 Oligonucleotides as Artificial DNases.- Section II: The Biology of Triple Helices.- 8 Potential Mechanisms of Action.- 9 Oligonucleotide Uptake and Delivery in Tissue Culture Cells.- 10 Triple-Stranded Complexes as Antigene Molecules: Transcription Inhibition Ex Vivo.- 11 Gene-Targeting Triple Helix Forming Purine Oligonucleotides.- 12 DNA Triple Helix as a Tool to Regulate Cytokine Gene Expression.- 13 Genome Modification by Triplex-Forming Oligonucleotides.- 14 Psoralen-Coupled Oligonucleotides: In Vivo Binding and Repair.- 15 Structure and Biology of H DNA.- 16 Triplex-Binding Proteins.- 17 RNA and Triple Helices.- Section III: New Developments and Applications.- 18 Triplexes Involving PNA.- 19 Triple Helix Stabilizing Agents.- 20 New Targets for Triple Helix Forming Oligonucleotides.- 21 Triplexes and Biotechnology.