The Functional Roles of Glial Cells in Health and Disease
Springer-Verlag New York Inc.
978-1-4613-7121-2 (ISBN)
I. Glial Cell Development.- 1. Developmental Regulation in the Schwann Cell Lineage.- 2. Transcriptional Regulation of the POU Gene Oct-6 in Schwann Cells.- 3. Glia Development in the Embryonic CNS of Drosophila.- 4. Role and Mechanism of Action of Glial Cell Deficient/Glial Cell Missing (Glide/gcm),the Fly Glial Promoting Factor.- II. Glia in Neurotransmission, Neuromodulation, and Neuron Survival.- 5. Expression and Functional Analysis of Glutamate Receptors in Glial Cells.- 6. Astrocytes as Active Participants of Glutamatergic Function and Regulators of Its Homeostasis.- 7. Glia-Neuron Interaction by High-Affinity Glutamate Transporters in Neurotransmission.- 8. On How Altered Glutamate Homeostasis May Contribute to Demyelinating Diseases of the CNS.- 9. Possible Role of Microglial Prostanoids and Free Radicals in Neuroprotection and Neurodegeneration.- III. Glia, Inflammation, and Cytokines.- 10. The Role of Microglia and Astrocytes in CNS Immune Surveillance and Immunopathology.- 11. The Role of Chemokines in the Pathogenesis of Multiple Sclerosis.- 12. Humoral and Cellular Immune Functions of Cytokine-Treated Schwann Cells.- 13. Axotomy-Induced Glial Reactions in Normal and Cytokine Transgenic Mice.- IV. Glia in CNS Plasticity and Regeneration.- 14. Contribution of Astrocytes to Activity-Dependent Structural Plasticity in the Adult Brain.- 15. The Role of Oligodendrocytes and Oligodendrocyte Progenitors in CNS Remyelination.- 16. Growth Promoting and Inhibitory Effects of Glial Cells in the Mammalian Nervous System.- 17. Neurite Outgrowth Inhibitors in Gliotic Tissue.- V. Transgenic Models of Human Myelin Diseases.- 18. Connexin32 in Hereditary Neuropathies.- 19. Genetic Analysis of Myelin Galactolipid function.- 20. Transgenic Models of TNF Induced Demyelination.- 21. Dysmyelination in Mice and the Proteolipid Protein Gene Family.- VI. Neuron-Glial Communications Neurotrophins and Cell Adhesion Molecules.- 22. Neurotrophins in Cell Survival/Death Decisions.- 23. Neuregulin in Neuron/Glial Interactions in the Central Nervous System: GGF2 Diminishes Autoimmune Demyelination, Promotes Oligodendrocyte Progenitor Expansion, and Enhances Remyelination.- 24. Adhesion Molecule Expression and Phenotype of Glial Cells in the Olfactory Tract.- 25. Bidirectional Signaling between Neurons and Glial Cells via the F3 Neuronal Adhesion Molecule.- VII. Connexins and Information Transfer through Glia.- 26. Connexins and Information Transfer through Glia.- 27. Gap Junctions in Glia: Types, Roles, and Plasticity.- 28. Metabolic Coupling and the Role Played by Astrocytes in Energy Distribution and Homeostasis.- 29. Consequences of Impaired Gap Junctional Communication in Glial Cells.- List of Contributors.
Reihe/Serie | Advances in Experimental Medicine and Biology ; 468 |
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Zusatzinfo | X, 389 p. |
Verlagsort | New York, NY |
Sprache | englisch |
Maße | 155 x 235 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie |
Studium ► 1. Studienabschnitt (Vorklinik) ► Anatomie / Neuroanatomie | |
Naturwissenschaften ► Biologie ► Humanbiologie | |
Naturwissenschaften ► Biologie ► Zoologie | |
ISBN-10 | 1-4613-7121-X / 146137121X |
ISBN-13 | 978-1-4613-7121-2 / 9781461371212 |
Zustand | Neuware |
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