Neural Circuit Development and Function in the Healthy and Diseased Brain

Dr. Rubenstein is a Professor in the Department of Psychiatry at the University of California, San Francisco. He also serves as a Nina Ireland Distinguished Professor in Child Psychiatry at the Nina Ireland Laboratory of Developmental Neurobiology. His research focuses on the regulatory genes that orchestrate development of the forebrain. Dr. Rubenstein's lab has demonstrated the role of specific genes in regulating neuronal specification, differentiation, migration and axon growth during embryonic development and on through adult life. His work may help to explain some of the mechanisms underlying human neurodevelopmental disorders such as autism. Dr. Rakic is currently at the Yale School of Medicine, Department of Neuroscience, where his main research interest is in the development and evolution of the human brain. After obtaining his MD from the University of Belgrade School of Medicine, his research career began in 1962 with a Fulbright Fellowship at Harvard University after which he obtained his graduate degrees in Developmental Biology and Genetics. He held a faculty position at Harvard Medical School for 8 years prior to moving to Yale University, where he founded and served as Chair of the Department of Neurobiology for 37 years, and also founder and director of the Kavli Institute for Neuroscience. In 2015, he returned to work full-time on his research projects, funded by US Public Health Services and various private foundations. He is well known for his studies of the development and evolution of the brain, in particular his discovery of basic cellular and molecular mechanisms of proliferation and migration of neurons in the cerebral cortex. He was president of the Society for Neuroscience and popularized this field with numerous lectures given in over 35 counties. In 2008, Rakic shared the inaugural Kavli Prize in Neuroscience with Thomas Jessell and Stan Grillner. He is currently the Dorys McConell Duberg Professor of Neuroscience and serves on Advisory Boards and Scientific Councils of a number of Institutions and Research Foundations.

I: Circuit Development 1. The Form and Functions of Neural Circuits in the Olfactory Bulb G. Lepousez, P.-M. Lledo 2. Functional Circuit Development in the Auditory System D.B. Polley, A.H. Seidl, Y. Wang, J.T. Sanchez 3. Development of the Superior Colliculus/Optic Tectum B.E. Stein, T.R. Stanford 4. Multisensory Circuits A.J. King 5. Cerebellar Circuits M. Kano, M. Watanabe 6. Dendritic Spines D. Muller, I. Nikonenko 7. Cortical Columns Z. Molnár 8. Neonatal Cortical Rhythms R. Khazipov, M. Colonnese, M. Minlebaev 9. Spike Timing-Dependent Plasticity D.E. Shulz, D.E. Feldman

II: Cognitive Development 10. Introduction to Cognitive Development from a Neuroscience Perspective H. Tager-Flusberg 11. Theories in Developmental Cognitive Neuroscience M.H. Johnson 12. Structural Brain Development: Birth Through Adolescence J.B. Colby, E.D. O'Hare, J.E. Bramen, E.R. Sowell 13. Statistical Learning Mechanisms in Infancy J. Lany, J.R. Saffran 14. Development of the Visual System S.P. Johnson 15. The Development of Visuospatial Processing J. Stiles, N. Akshoomoff, F. Haist 16. Memory Development P.J. Bauer 17. Early Development of Speech and Language: Cognitive, Behavioral, and Neural Systems H. Tager-Flusberg, A.M. Seery 18. The Neural Architecture and Developmental Course of Face Processing G. Righi, C.A. Nelson III 19. Developmental Neuroscience of Social Perception A. Voos, C. Cordeaux, J. Tirrell, K. Pelphrey 20. Developmental Cognitive Neuroscience of Theory of Mind H. Gweon, R. Saxe 21. A Neuroscience Perspective on Empathy and Its Development J. Decety, K.J. Michalska 22. Developing Attention and Self-Regulation in Infancy and Childhood M.I. Posner, M.K. Rothbart, M.R. Rueda 23. The Neural Correlates of Cognitive Control and the Development of Social Behavior A. Lahat, N.A. Fox 24. Executive Function: Development, Individual Differences, and Clinical Insights C. Hughes 25. The Effects of Stress on Early Brain and Behavioral Development M.R. Gunnar, E.P. Davis 26. Sex Differences in Brain and Behavioral Development A.M. Beltz, J.E.O. Blakemore, S.A. Berenbaum

III: Diseases 27. Neural-Tube Defects C. Pyrgaki, L. Niswander 28. Fetal Alcohol Spectrum Disorder: Targeted Effects of Ethanol on Cell Proliferation and Survival S.M. Mooney, P.J. Lein, M.W. Miller 29. Azetidine-2-Carboxylic Acid and Other Nonprotein Amino Acids in the Pathogenesis of Neurodevelopmental Disorders E. Rubenstein 30. Down Syndrome A.B. Bowman, K.C. Ess, K.K. Kumar, K.L. Summar 31. Lissencephalies and Axon Guidance Disorders E.H. Sherr, L. Fernandez 32. Developmental Disabilities, Autism, and Schizophrenia at a Single Locus: Complex Gene Regulation and Genomic Instability of 15q11–q13 Cause a Range of Neurodevelopmental Disorders N. Urraca, L.T. Reiter 33. Fragile X Clinical Features and Neurobiology M.J. Leigh, R.J. Hagerman 34. Autisms M. Persico 35. Neurodevelopmental Genomics of Autism, Schizophrenia, and Related Disorders J.F. Cubells, D. Moreno-De-Luca 36. Excitation–Inhibition Epilepsies A.X. Thomas, A.R. Brooks-Kayal 37. Sensory Organ Disorders (Retina, Auditory, Olfactory, Gustatory) D.C. Gillespie 38. The Developmental Neurobiology of Repetitive Behavior S.-J. Kim, M. Lewis, J. Veenstra-VanderWeele 39. Disorders of Cognitive Control B.J. Casey, N. Franklin, M.M. Cohen 40. Language Impairment R.H. Fitch Index