Infectious Agents and Cancer (eBook)

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2012 | 2013
X, 118 Seiten
Springer Netherland (Verlag)
978-94-007-5955-8 (ISBN)

Lese- und Medienproben

Infectious Agents and Cancer - Anton G. Kutikhin, Arseniy E. Yuzhalin, Elena B. Brusina
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​Over the years of cancer investigation a lot of discoveries in this field were made, and many associations between various biological carcinogens and cancer were revealed. Some of them are credibly determined, thus these infectious agents (human papilloma virus, hepatitis B virus, hepatitis C virus, Epstein-Barr virus, human herpes virus 8, human T-cell lymphotropic virus 1, human immunodeficiency virus, Merkel cell polyomavirus, Helicobacter pylori, Opisthorchis viverrini, Clonorchis sinensis, Schistosoma haematobium) are recognized as carcinogens and probable carcinogens by International Agency for Research on Cancer (IARC). The problem is of large importance, since share of infectious agents-related cancer cases is steadily increasing, reaching 25% according to certain estimates. It is worth noting that many of cancer cases are caused by infectious agents other than «conventional ones» like HPV, EBV, HBV, HCV, H.pylori etc. In recent years, a number of significant breakthroughs in the field were performed, such as the discovery of the microbiota role in cancer causation.
?Over the years of cancer investigation a lot of discoveries in this field were made, and many associations between various biological carcinogens and cancer were revealed. Some of them are credibly determined, thus these infectious agents (human papilloma virus, hepatitis B virus, hepatitis C virus, Epstein-Barr virus, human herpes virus 8, human T-cell lymphotropic virus 1, human immunodeficiency virus, Merkel cell polyomavirus, Helicobacter pylori, Opisthorchis viverrini, Clonorchis sinensis, Schistosoma haematobium) are recognized as carcinogens and probable carcinogens by International Agency for Research on Cancer (IARC). The problem is of large importance, since share of infectious agents-related cancer cases is steadily increasing, reaching 25% according to certain estimates. It is worth noting that many of cancer cases are caused by infectious agents other than conventional ones like HPV, EBV, HBV, HCV, H.pylori etc. In recent years, a number of significant breakthroughs in the field were performed, such as the discovery of the microbiota role in cancer causation.

Preface1 The Criteria of Inclusion of Infectious Agents in the List of  Biological Carcinogens2 General Mechanisms of Biological Carcinogenesis2.1 Metabolic mechanisms2.2 Immune mechanisms2.3 Mechanisms mediated by the carcinogenic activity of the bacterial and protozoan toxins3 The Role of Bacteria in Cancer Development3.1 The Role of Bacteria in Cancer of the Digestive Tract3.2 The Role of Bacteria in Cancer of the Respiratory3.3 The Role of Bacteria in Cancer of the Genitourinary Tract3.4 The Role of Bacteria in Cancer of the Hematolymphopoietic Tract3.5 Additional Bacteria Anecdotally Associated with Cancer4 The Role of Protozoa in Cancer Development4.1 Toxoplasma gondii4.2 Cryptosporidium parvum4.3 Trichomonas vaginalis5 The Role of Helminths and Fungi in Cancer Development5.1 Taenia spp5.2 Strongyloides stercoralis.5.3 Fasciola hepatica, Trichostrongylus colubriformis, Paracoccidioides brasiliensis.6 Organ Microbiota in Cancer Development: the Holy Grail of Biological Carcinogenesis6.1 The Role of Oral Microbiota in Cancer Development6.2 The Role of Gut Microbiota in Colorectal Cancer Development7 Conclusions: Are We There Yet?

Erscheint lt. Verlag 5.12.2012
Zusatzinfo X, 118 p.
Verlagsort Dordrecht
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Technik
Schlagworte biological carcinogens and cancer • carcinogens and probable carcinogens • Infectious Agents • International Agency for Research on Cancer
ISBN-10 94-007-5955-X / 940075955X
ISBN-13 978-94-007-5955-8 / 9789400759558
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