Oxidative Stress in Vertebrates and Invertebrates: Molecular Aspects of Cell Signaling

TAHIRA FAROOQUI has published extensively on drug receptor interactions, biogenic amines in vertebrate and invertebrate nervous systems, glycerophospholipid and sphingolipid metabolism, and molecular mechanisms in the brain, as well as on the neuromodulatory role of octopamine in the reinforcement pathway involved in olfactory learning and memory. AKHLAQ A. FAROOQUI is a leader in the fields of signal transduction, brain phospholipase A 2 , bioactive ether lipid metabolism, and polyunsaturated fatty acid metabolism, among others. Farooqui has published on the generation and identification of glycerophospholipid-, sphingolipid-, and cholesterol-derived lipid mediators in kainic acid-mediated neurotoxicity by lipidomics.

PREFACE xi Tahira Farooqui and Akhlaq A. Farooqui FOREWORD xiii Grace Y. Sun ACKNOWLEDGMENTS xv Tahira Farooqui and Akhlaq A. Farooqui CONTRIBUTORS xvii PART I OXIDATIVE STRESS IN VERTEBRATES 1 Generation of Reactive Oxygen Species in the Brain: Signaling for Neural Cell Survival or Suicide 3 Akhlaq A. Farooqui 2 Free Radicals, Signal Transduction, and Human Disease 17 Klaudia Jomova and Marian Valko 3 Oxidative Stress and its Biochemical Consequences in Mitochondrial DNA Mutation-Associated Diseases: Implications of Redox Therapy for Mitochondrial Diseases 33 Shi-Bei Wu, Yu-Ting Wu, Yi-Shing Ma, and Yau-Huei Wei 4 Oxidative Stress in Kainic Acid Neurotoxicity: Implications for the Pathogenesis of Neurotraumatic and Neurodegenerative Diseases 51 Akhlaq A. Farooqui 5 Survival Strategy and Disease Pathogenesis According to the Nrf2-Small Maf Heterodimer 63 Masanobu Morita and Hozumi Motohashi 6 Caloric Restriction and Oxidative Stress 83 Jan Skrha 7 Pathogenesis of Neurodegenerative Diseases: Contribution of Oxidative Stress and Neuroinflammation 103 Tahira Farooqui and Akhlaq A. Farooqui 8 Neurosteroids in Oxidative Stress-Mediated Injury in Alzheimer Disease 117 Amandine Grimm, Ayikoe Guy Mensah-Nyagan, and Anne Eckert 9 Oxidative Stress in Adult Neurogenesis and in the Pathogenesis of Alzheimer Disease 129 Philippe Taupin 10 Oxidative Stress and Parkinson Disease 139 Kah-Leong Lim, Doyle Graham, and Xiao-Hui Ng 11 Oxidative Stress in Cardiovascular Diseases 153 Michael E. Andrades and Rodrigo Lorenzi 12 Oxidative Stress and Aging: A Comparison between Vertebrates and Invertebrates 167 Syed Ibrahim Rizvi and Kanti Bhooshan Pandey 13 Oxidative Stress-Mediated Signaling Pathways by Environmental Stressors 175 Hideko Sone and Hiromi Akanuma 14 Selenoproteins in Cellular Redox Regulation and Signaling 195 Arjun V. Raman and Marla J. Berry 15 Antioxidant Therapy and its Effectiveness in Oxidative Stress-Mediated Disorders 209 Tommaso Iannitti and Beniamino Palmieri 16 The Protective Role of Grape Seed Polyphenols Against Oxidative Stress in Treating Neurodegenerative Diseases 235 Giulio Maria Pasinetti 17 Pharmacological and Therapeutic Properties of Propolis (Bee Glue) 245 Kandangath Raghavan Anilakumar, Farhath Khanum, and Amarinder Singh Bawa PART II OXIDATIVE STRESS IN INVERTEBRATES 18 Endocrine Control of Oxidative Stress in Insects 261 Natraj Krishnan and Dalibor Kodri'k 19 Oxidative Stress in the Airway System of the Fruit Fly Drosophila melanogaster 271 Thomas Roeder 20 Molecular Mechanisms of Antioxidant Protective Processes in Honeybee Apis mellifera 279 Alexey G. Nikolenko, Elena S. Saltykova, and Louisa R. Gaifullina 21 Molecular Basis of Iron-induced Oxidative Stress in the Honeybee Brain: A Potential Model System of Olfactory Dysfunction in Neurological Diseases 295 Tahira Farooqui 22 Modulation of Oxidative Stress by Keap1/Nrf2 Signaling in Drosophila: Implications for Human Diseases 309 Gerasimos P. Sykiotis, M. Mahidur Rahman, and Dirk Bohmann 23 Orchestration of Oxidative Stress Responses in Drosophila melanogaster: A Promoter Analysis Study of Circadian Regulatory Motifs 327 Kuntol Rakshit and Natraj Krishnan 24 The Protective Role of Sestrins Against Chronic TOR Activation and Oxidative Stress 337 Jun Hee Lee and Ethan Bier 25 Current Advances in the Studies of Oxidative Stress and Age-Related Memory Impairment in C. elegans 347 Shin Murakami, Kelly Cabana, and Danielle Anderson 26 Oxidative Challenge and Redox Sensing in Mollusks: Effects of Natural and Anthropic Stressors 361 Julie Letendre, FrancCois Leboulenger, and Fabrice Durand 27 Perspective and Directions for Future Studies 377 Tahira Farooqui and Akhlaq A. Farooqui INDEX 385