Myeloproliferative Neoplasms -

Myeloproliferative Neoplasms

Biology and Therapy
Buch | Softcover
230 Seiten
2012
Humana Press Inc. (Verlag)
978-1-61779-711-8 (ISBN)
181,89 inkl. MwSt
This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs. Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments.

Chapter 1 - Diagnosis and Classification of the BCR-ABL-negative Myeloproliferative Neoplasms.- Chapter 2 - Genetics of the Myeloproliferative Neoplasms.- Chapter 3 - Cytogenetic Findings in Classic Myeloproliferative Neoplasms.- Chapter 4 - Prognostic Factors in Classic Myeloproliferative Neoplasms.- Chapter 5 - Therapy of Polycythemia Vera and Essential Thrombocythemia.- Chapter 6 - Conventional and Investigational Therapy for Primary Myelofibrosis.- Chapter 7 - Hematopoietic Cell Transplantation for Myelofibrosis.- Chapter 8 - JAK2 Inhibitors as Therapy for Classic Myeloproliferative Neoplasms.- Chapter 9 - Blastic Transformation of Classic Myeloproliferative Neoplasms.- Chapter 10 - Eosinophilic Disorders: Differential Diagnosis and Management.- Chapter 11 - Pathogenesis, Diagnosis, Classification, and Management of Systemic Mastocytosi.

Reihe/Serie Contemporary Hematology
Zusatzinfo X, 230 p.
Verlagsort Totowa, NJ
Sprache englisch
Maße 178 x 254 mm
Themenwelt Medizinische Fachgebiete Innere Medizin Hämatologie
Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Naturwissenschaften Biologie Biochemie
Schlagworte disorders • Eosinophilic • JAK2 • leukemia • mastocytosis • MPL • Mutation • Myelofibrosis • Myeloid • Myeloproliferative • Neoplasms • Polycythemia • Throbocythemia
ISBN-10 1-61779-711-1 / 1617797111
ISBN-13 978-1-61779-711-8 / 9781617797118
Zustand Neuware
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