Chembiomolecular Science (eBook)

Part 1 Chembiomolecular Chemistry. Chemistry of Mycolactones, the Causative Toxins of Buruli Ulcer.- Practical Synthesis of Tamiflu and Beyond.- An Approach Toward Identification of Target Proteins of Maitotoxin Based on Organic Synthesis.- Inhibitors of Fatty Acid Amide Hydrolase.- Small Molecule Tools for Cell Biology and Cell Therapy.- Toward the Discovery of Small Molecules Affecting RNA Function.- New Insights from a Focused Library Approach Aiming at Development of Inhibitors of Dual-Specificity Protein Phosphatases.- The Deep Oceans as a Source for New Treatments for Cancer.- Search for New Medicinal Seeds from Marine Organisms.- Identification of Protein–Small Molecule Interactions by Chemical Array.- Part 2 Chembiomolecular Biology. Small Molecule-Induced Proximity.- High-Throughput Screening for Small Molecule Modulators of FGFR2-IIIb Pre-mRNA Splicing.- Identification of Signaling Pathways That Mediate Dietary Restriction-Induced Longevity in Caenorhabditis elegans.- Roles for the Stress-Responsive Kinases ASK1 and ASK2 in Tumorigenesis.- Tailored Synthetic Surfaces to Control Human Pluripotent Stem Cell Self-Renewal.- Cell-Surface Glycoconjugates Controlling Human T-Lymphocyte Homing: Implications for Bronchial Asthma and Atopic Dermatitis.- Establishment of a Novel System for Studying the Syk Function in B Cells.- Visual Screening for the Natural Compounds That Affect the Formation of Nuclear Structures.- Versatile Orphan Nuclear Receptor NR4A2 as a Promising Molecular Target for Multiple Sclerosis and Other Autoimmune Diseases.- Antiviral MicroRNA. - Synaptic Function Monitored Using Chemobiomolecular Indicators.- Part 3 Chembiomolecular Medicinal Chemistry. Practical Catalytic Asymmetric Synthesis of a Promising Drug Candidate.- Hunting the Targets of Natural Product-Inspired Compounds.- Chemical Approaches for Understanding and Controlling Infectious Diseases.- Nongenomic Mechanism-Mediated Renal Fibrosis-Decreasing Activity of a Series of PPAR-g Agonists.- Novel Carbohydrate-Based Inhibitors That Target Influenza A Virus Sialidase.- Multidrug Efflux Pumps and Development of Therapeutic Strategies to Control Infectious Diseases.- Enzymes as Chemotherapeutic Agents.- Mechanism of Action of New Antiinfectious Agents from Microorganisms.- Correction of RNA Splicing with Antisense Oligonucleotides as a Therapeutic Strategy for a Neurodegenerative Disease.- Modulation of Pre-mRNA Splicing Patterns with Synthetic Chemicals and Their Clinical Applications.