Extracellular Nucleic Acids -

Extracellular Nucleic Acids

Yo Kikuchi, Elena Y. Rykova (Herausgeber)

Buch | Softcover
XII, 232 Seiten
2012 | 2010
Springer Berlin (Verlag)
978-3-642-26419-1 (ISBN)
160,49 inkl. MwSt
Following their emergence as key players in biology and the medical sciences, this book covers newly developing fields related to extracellular nucleic acids, including their basic biology, their ecology and their implications for medical science.
Extracellular nucleic acids have recently emerged as important players in the fields of biology and the medical sciences. In the last several years, extracellular nucleic acids have been shown to be involved in not only microbial evolution as genetic elements but also to have structural roles in bacterial communities, such as biofilms. Circulating DNA and RNA have been found in human blood and expected to be useful as non-invasive markers for the diagnosis of several diseases. In addition, extracellular nucleic acids have attracted attention as active modulators of the immune system of higher organisms, including humans.This book covers nearly all of the newly developing fields related to extracellular nucleic acids, including those of basic biology, ecology and the medical sciences, and provides readers with the latest knowledge on them.

Extracellular DNA as matrix component in microbial biofilms.- Gene transfer agents and defective bacteriophages as sources of extracellular prokaryotic DNA.- Roles of extracellular DNA in bacterial ecosystem.- Stable extracellular DNA: a novel substrate for genetic engineering that mimics horizontal gene transfer in nature.- Extracellular nucleic acids of the marine phototrophic bacterium Rhodovulum sulfidophilum and related bacteria: physiology and biotechnology.- Systemic RNAi in C. elegans from the viewpoint of RNA as extracellular signals.- Circulating nucleic acids in health and disease.- Extracellular microRNAs/small RNAs in cancer pathogenesis and diagnostics.- Biology and diagnostic applications of cell-free fetal nucleic acids in maternal plasma.- The biology of circulating nucleic acids in plasma and serum (CNAPS).- Modulation and regulation of gene expression by CpG oligonucleotides.- Immune recognition of nucleic acids and their metabolites.

Erscheint lt. Verlag 5.9.2012
Reihe/Serie Nucleic Acids and Molecular Biology
Zusatzinfo XII, 232 p. 34 illus.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 374 g
Themenwelt Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
Schlagworte DNA • Evolution • gene expression • genes • Genetic Engineering • gene transfer • immune system • Nucleotide • Physiology • Regulation • RNA
ISBN-10 3-642-26419-0 / 3642264190
ISBN-13 978-3-642-26419-1 / 9783642264191
Zustand Neuware
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