The Adrenocortical Hormones

Professor Helen Wendler Deane Markham, 1917-1966.- 9: Control of Aldosterone Secretion.- Methods Used to Measure the Rate of Aldosterone Secretion.- Effccts of Changes in Plasma Electrolyte Levels on Aldosterone Secretion.- ACTH and the Control of Aldosterone Secretion.- The Renin-Angiotensin System and the Control of Aldosterone Secretion.- Interactions Between ACTH and Angiotensin II.- Possible Neural Regulatory Mechanisms.- Effect of Growth Hormone on Aldosterone Secretion.- Effects of Other Hormones on Aldosterone Secretion.- Stimuli Affecting Aldosterone Secretion and Probable Pathways through which they Exert their Effects.- Effects of Variations in Aldosterone Metabolism on Aldosterone Secretion.- Relation between Aldosterone Secretion and the Autonomic Nervous System.- Other Mechanisms Regulating Sodium and Potassium Excretion.- Conclusions.- Appendix: Chemical Names for Substances Mentioned in Text.- Literature.- 10: Manifestations of Hypersecretion of Adrenal Sex Steroids in Man..- The Human Fetus.- Pseudohermaphroditism.- Congenital Adrenal Hyperplasia.- Acquired Syndromes.- Testosterone Determinations in Biological Fluids.- Literature.- 11: Control of Corticotrophin Secretion.- The Assessment of Hypothalamo-Pituitary-Adrenocortical Activity.- Regulation of Pituitary Adrenocorticotrophic Activity.- Conclusion.- Literature.- 12: On the Pharmacologic Actions of 21-Carbon Hormonal Steroids ("Glucocorticoids") of the Adrenal Cortex in Mammals.- General Considerations.- Mechanism of Action of Glucocorticoids.- Action of Glucocorticoids on Enzymes and Lysosomes.- Action of Glucocorticoids on Cells, Tissues, Organs and Systems.- Pharmacologic Actions of Glucocorticoids in Man.- Literature.