Alzheimer’s Disease: Lessons from Cell Biology
Springer Berlin (Verlag)
978-3-642-79425-4 (ISBN)
Endocytotic Pathways in Neurons.- Mechanisms of Molecular Sorting in Polarized Cells: Relevance to Alzheimer's Disease.- Regulation of Receptor Trafficking by ras-Like GTPases.- Alzheimer's Disease and Hemorrhagic Stroke: Their Relationship to ?A4 Amyloid Deposition.- Combining In Vitro Cell Biology and In Vivo Mouse Modelling to Study the Mechanisms Underlying Alzheimer's Disease.- Implication of the Amyloid Precursor Protein in Neurite Outgrowth.- Physiological Production and Polarized Secretion of the Amyloid ?-Peptide in Epithelial Cells: A Route to the Mechanism of Alzheimer's Disease.- Regulation and Structure of the MAP Kinases ERK1 and ERK2.- Calcineurin as a Pivotal Ca2+-Sensitive Switching Element in Biological Responses: Implications for the Regulation of Tau Phosphorylation in Alzheimer's Disease.- Phosphorylation of Tau and Its Relationship with Alzheimer Paired Helical Filaments.- Posttranslational Modifications of the Tau in PHF: Phosphorylation and Ubiquitination.- Tau Variants in Aging and Neurodegenerative Disorders.- A Phosphorylated Tau Species Is Transiently Present in Developing Cortical Neurons and Is Not Associated with Stable Microtubules.- Modifications of Phosphorylated Tau Immunoreactivity Linked to Excitotoxicity in Neuronal Cultures.- Neurofilaments and Motor Neuron Disease.- Lurcher, Cell Death and the Cell Cycle.- Neuronal Death, Proinflammatory Cytokines and Amyloid Precursor Protein: Studies on Staggerer Mutant Mice.- Amyloid ?-Peptide Induces Necrotic Cell Death in PC12 Cells.- Linking Amyloid Precursor Protein Processing and Tau-Related Pathology in Alzheimer's Disease.
Erscheint lt. Verlag | 31.12.2011 |
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Reihe/Serie | Research and Perspectives in Alzheimer's Disease |
Zusatzinfo | XIX, 243 p. 39 illus., 1 illus. in color. |
Verlagsort | Berlin |
Sprache | englisch |
Maße | 155 x 235 mm |
Gewicht | 410 g |
Themenwelt | Naturwissenschaften ► Biologie ► Humanbiologie |
Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
Naturwissenschaften ► Biologie ► Zellbiologie | |
Schlagworte | aging • Alzheimer • Alzheimer's disease • Amyloid precursor protein • Biology • Cell • Cell Biology • cellular processes • Hemorrhagic stroke • neurodegenerative disorders • proteins |
ISBN-10 | 3-642-79425-4 / 3642794254 |
ISBN-13 | 978-3-642-79425-4 / 9783642794254 |
Zustand | Neuware |
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