Cellular and Molecular Basis of Synaptic Transmission

Development of the Subject and State of the Art.- The Cellular Basis of Synaptic Transmission: An Overview.- Structural Organization of the Synapse and Dynamics of Synaptic Organelles.- Specializations of Subsynaptic Cytoplasms. Comparison of Axospinous Synapses and Neuromuscular Junctions.- New Evidence Supporting the Vesicle Hypothesis for Quantal Secretion at the Neuromuscular Junction.- Poststimulation Increase of Synaptic Vesicle Number in the Preganglionic Nerve Terminals of the Cat Sympathetic Ganglion In Vitro.- Synaptic Vesicle Classes in Torpedo and Skate Electric Organ and Muscle.- Effect of Nerve Stimulation, K+ Saline and Hypertonic Saline on Classes of Quanta, Quantal Content and Synaptic Vesicle Size Distribution of Torpedo Electric Organ.- Fine Structural Correlates of Calcium Dynamics in the Presynaptic Terminal.- Differential Release of Transmitters and Neuropeptides Co-Stored in Central and Peripheral Neurons.- Presynaptic Regulation of Transmitter Synthesis and Release.- The Detection, Isolation and Properties of Sub-Populations of Mammalian Brain Synaptosomes of Defined Neurotransmitter Type.- Excitatory Amino Acids; Physiology, Anatomy and Biochemistry.- Synaptosomal Bioenergetics and the Mechanism of Amino Acid Transmitter Release.- Heterologous Carriers Located on Rat CNS Nerve Endings and their Possible Role in the Modulation of Transmitter Release.- Spontaneous Release of Acetylcholine from Torpedo Electromotor Neurons.- The Mechanism of Acetylcholine Release: Its Essential Component, the Mediatophore.- Structure and Function of Presynaptic Ion Channels.- Potassium Channels in Rat Brain Synaptosomes: Pharmacology and Toxicology.- Calcium Channels and Na+/Ca2+Exchange in Synaptosomes.- Properties of Presynaptic Voltage-Sensitive Calcium Channelsin Rat Synaptosomes.- Mechanisms of Failure of Synaptic Transmission During Anoxia.- Molecular and Functional Organization of Synaptic Vesicles.- Adrenergic and Cholinergic Vesicles: Are there Common Antigens and Common Properties?.- Structure and Function of Synaptic Vesicles: New Aspects.- Complexity and Regulation in the Acetylcholine Storage System of Synaptic Vesicles.- Synaptic Vesicle Proteins.- Synaptophysin: a Major Cell Type-Specific Vesicle Protein of Neuroendocrine Cells.- Cotransmitters: Cellular Location, Function and Metabolism.- The New Paradigm: Sympathetic Neurotransmission by Lateral Interaction between Single Mixed Quanta Acting in Two Different Biophases.- Sympatho-Adrenal Co-Storage, Release and Synthesis of Enkephalins and Catecholamines Induced by Acute CNS Ischemia in Pig.- Extracellular Metabolism of ATP at the Cholinergic Electromotor Synapse: Characterization and Location of Ectonucleotidases.- The Application of Immunoaffinity Techniques to the Study of Cholinergic Neurobiology.- Transmitter/Modulator Induced Events Related to Excitation-Contraction Coupling in Skeletal Muscle of Vertebrates. Action of ATP.- Identity and Functional Role of Neuropeptides in Torpedo Electric Organ.- Neurotransmitter Receptors.- Mechanisms Regulating the Expression and Function of Acetylcholine Receptor.- Antibodies as Probes of the Structure of the Nicotinic Acetylcholine Receptor.- Brain ?-Neurotoxin-Binding Proteins and Nicotinic Acetylcholine Receptors.- Human Neuroblastoma Cells: An In Vitro Model for the Study of Mammalian Neuronal Nicotinic Receptors.- Molecular Biology Approaches to the Function and Development of CNS Synapses.- Recent Studies on Opioid Receptors.